Project Manager, Clinical Operations US; On-site​/Remote

REV Clinical (formerly CBCC Global Research)

REV Clinical is seeking an experienced and highly motivated Project Manager to independently lead and oversee the operational execution of domestic and global clinical trials. The Project Manager serves as the primary point of contact for sponsors and internal cross-functional teams and is accountable for achieving study objectives related to timelines, quality, budget, and patient enrollment.

This role requires a proactive leader with strong project management expertise, exceptional client-facing skills, and demonstrated success managing Phase I-IV clinical studies within a CRO environment. Experience in Oncology is strongly preferred, with additional experience in Neurology, Ophthalmology, or Rare Disease considered a strong asset.

The ideal candidate thrives in a fast-paced, entrepreneurial environment and is passionate about delivering clinical trials with reliability, excellence, and velocity.

On-site and/or Remote

REV Clinical (formerly CBCC Global Research), headquartered in Bakersfield, California with additional operations in Ahmedabad, India and Australia is a leading, multi-national clinical contract research organization with deep experience in designing and managing clinical trials across a range of therapeutic areas, including Oncology, CNS, and Ophthalmology. REV Clinical provides end-to-end CRO services — spanning clinical study design, project management, data analysis, regulatory strategy and medical writing— across Phase I–IV clinical trials for leading biopharmaceutical companies.

REV Clinical is seeking an experienced and highly motivated Project Manager to independently lead and oversee the operational execution of domestic and global clinical trials. The Project Manager serves as the primary point of contact for sponsors and internal cross-functional teams and is accountable for achieving study objectives related to timelines, quality, budget, and patient enrollment.

• Independently lead one or more Phase I-IV clinical studies from study startup through closeout.
• Serve as the primary operational contact for sponsors, investigators, sites, and internal teams.
• Develop and maintain comprehensive project plans, timelines, study forecasts, and risk mitigation strategies.
• Ensure project milestones, deliverables, and quality standards are achieved according to client expectations and contractual obligations.
• Lead study team meetings and drive accountability across cross-functional departments.
• Monitor study progress and identify operational risks, proposing solutions before issues impact timelines or quality.
• Support inspection readiness and ensure that projects are conducted in accordance with applicable regulations and company SOPs.

• Build strong working relationships with sponsor teams and serve as a trusted strategic and operational partner.
• Provide regular project status updates, study metrics, risk assessments, and executive summaries.
• Lead sponsor meetings, governance discussions, and project reviews.
• Support proposal development, scope discussions, and change order management as needed.
• Participate in bid defense meetings and business development opportunities when requested.
• Manage project budgets, forecasts, and financial performance.
• Monitor revenue recognition, study burn rates, and overall project profitability.
• Review project resourcing needs and collaborate with departmental leadership to ensure appropriate staffing.
• Identify potential scope changes and support timely change order development.

• Coordinate activities across…