Senior Clinical Project Manager

Sr. Clinical Project Manager (Home-Based / 100% Remote)

Join a growing global CRO and lead the successful delivery of complex clinical trials from start-up through closeout. As a Sr Clinical Project Manager, you will serve as the primary client contact, overseeing study execution, timelines, budgets, quality, and cross-functional teams to ensure projects are delivered on time, within scope, and to the highest standards.

Must Have: 4+ years of recent Clinical Project Management experience within a CRO environment, cannot be FSP embedded.

• Serve as the primary client contact and escalation point for assigned studies.
• Lead cross-functional teams to deliver clinical trials on time, within budget, and in compliance with quality standards.
• Develop and maintain project plans, timelines, risk mitigation strategies, and study metrics.
• Manage study budgets, forecasting, profitability, and scope changes, including change orders.
• Oversee vendors and functional partners to ensure successful study delivery.
• Lead client meetings, project governance, and study status reporting.
• Identify and proactively manage project risks, issues, and protocol-related challenges.
• Ensure inspection readiness, eTMF quality, and adherence to regulatory and SOP requirements.
• Support bid defenses, business development activities, and client presentations as needed.
• Mentor team members and provide leadership across project teams.

• Bachelor's degree in a life science, health-related field, or equivalent experience.
• Minimum 7 years of clinical research experience.
• Minimum 4 years of project management experience within a full-service CRO.
• Proven experience managing global or multi-site clinical trials.
• Strong understanding of clinical trial operations, study start-up, risk management, and quality oversight.
• Demonstrated experience managing study budgets, forecasting, and financial performance.
• Excellent client-facing communication, presentation, and leadership skills.
• Ability to manage multiple priorities in a fast-paced environment.
• Willingness to travel domestically and internationally as needed.

• Experience leading complex Phase I-IV clinical trials.
• Experience in oncology, radiopharmaceuticals, cell therapy, or other complex therapeutic areas.
• Experience participating in bid defenses and business development initiatives.
• Strong knowledge of eTMF management, inspection readiness, and quality management processes.
• Experience working with global study teams, vendors, and sponsors.

This is a Permanent position based out of Frederick, MD.

The pay range for this position is $147300.00 - $200000.00/yr.

Individual compensation offered for this position within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, geographic location, internal equity, and other pertinent job-related factors.

Comprehensive Medical, Dental & Vision Coverage
- Generous employer contributions for employees and dependents, national Aetna plans, telehealth access, Delta Dental PPO options, and VSP vision coverage. 401(k) with Strong Employer Match - 4% employer match plus immediate 100% vesting through a Safe Harbor plan. Flexible Time Off
- Exempt employees receive uncapped "My Time" (MTO), while non-exempt employees receive 20 days PTO annually, paid holidays, personal days, and volunteer time off. Family Planning & Parental Support
- Infertility coverage, 8 weeks of paid maternity leave at 100% pay, 4 weeks of paid parental bonding leave, and up to $3,000 in adoption assistance per child. Company-Paid Life & Disability Insurance
- Basic life insurance and AD&D up to 1.5x salary (maximum $500,000) plus short- and long-term disability coverage at 60% of pay. Health Savings Account (HSA) Contributions
- Employees enrolled in the HDHP receive annual employer HSA contributions of $1,000 (individual) or $1,500 (family/employee-plus coverage). Wellness & Employee Assistance Programs
- Free 24/7 support through Headspace, including mental health resources, counseling support, legal/financial assistance, work-life services, and access to over 3,000 wellness resources

This is a Permanent position based out of Frederick, MD.

This position is anticipated to close on Nov 15, 2026.

This is a fully remote position.

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