Analytical Project Leader; Scientist​/Senior Scientist

Analytical Project Leader (Scientist / Senior Scientist)

We are currently looking for an Analytical Project Leader for a 12-month contract based in Basel, Switzerland.

2 days a week home office possible after onboarding.

The Analytical Research & Development department is a key part of Synthetic Molecules Technical Development. It is globally responsible for advancing analytical methodologies, performing in-depth analyses of active pharmaceutical ingredients, and diverse dosage forms, as well as preparing detailed regulatory documentation for submission to health authorities.

In this role, you will join a motivated and experienced team of analytical scientists. You will lead the analytical development of synthetic molecule projects involving small molecules, from early development to commercialization. This role offers a unique opportunity to apply your expertise in a dynamic, fast-paced environment and contribute to the development of life-changing medicines.

• Develop a phase-appropriate control strategy for drug substances and drug products.
• Collaborate effectively with stakeholders across various departments.
• Coordinate comprehensive analytical activities, which involves generating physical and chemical data for materials, developing/improving and validating analytical test methods or other analytical controls and ensuring thorough documentation, timely delivery and adherence to quality standards.
• Coach technicians and junior scientists on project work and serve as a central point of contact for project-related information.
• Conduct work in compliance with cGMP where applicable, safety, and regulatory requirements.
• Supervise internal laboratory activities and/or testing activities at CLOs/CDMOs.
• Plan and document experiments/results independently and prepare for regulatory submissions such as IND and NDA.

• Relevant working/residency permit or Swiss/EU-Citizenship required.
• Highly skilled and experienced Analytical Chemist with a strong background in small molecule analysis.
• Master’s or Ph.D. in chemistry, pharmacy, or a related field, with at least three years of professional experience in analytical development of drug substances or drug products for small molecules.
• In-depth knowledge of chemistry, including synthesis, purification, and characterization.
• Expertise in key analytical techniques such as High-Performance Liquid Chromatography (HPLC), Ultra-Performance Liquid Chromatography (UPLC).
• Proven experience in developing and validating ICH-compliant analytical methods.
• Proficiency in degradation and stability studies for small molecules, including forced degradation and impurity profiling.
• Understanding of key requirements for drug substances and drug product specifications.
• Excellent command of the English language.
• A strong quality mindset and excellent attention to detail.
• Digital savviness to support digital transformation initiatives; familiarity with statistical analysis of analytical data is also advantageous.
• Proficiency in German is a nice to have.