Research/Development Technician, Research Scientist
Sheffield, South Yorkshire, S5, England, UK
Listed on 2026-08-18
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Research/Development
Research Scientist, Biomedical Science
Overview
We are seeking technician to join our multidisciplinary team studying how the immune system controls infection. Cryptococcal meningitis (CM) is fungal infection of immunocompromised responsible for >100, 000 deaths globally each year and 20% of AIDS related deaths. In this project, we are studying a new way that macrophage immune cells can ingest and kill Cryptococcus. We have discovered that macrophages have sub-micron ridges on their surface which enhances their ability to interact and phagocytose Cryptococcus.
You will have a degree and research laboratory experience in biology or a related discipline (or equivalent experience) and be proficient in a variety of relevant techniques (e.g. cell culture, microbiology, molecular biology). Previous experience working with in vivo models is desirable but not essential. The project will include live imaging of host pathogen interactions in vitro, ex vivo and in vivo.
You will be able to contribute significantly to the ongoing research of the Johnston lab, by supporting, enabling and performing experiments along with the team. You will become a member of a passionate scientific research team that aims to understand fundamental aspects of biology relating to human disease. Your career development will be well supported and your development as a research scientist will be encouraged.
Duties And Responsibilities
- Laboratory management of biosafety level 2 laboratories, including safety and lab rule adherence, equipment and space booking systems, maintaining stock levels, external ordering and organising equipment maintenance.
- Maintain a safe working environment, including ensuring compliance with legislation and undertaking of risk assessments.
- Support and enable host pathogen interactions experiments in diverse experimental models of infection and immunity.
- Work as part of a multidisciplinary team across human infection, in vivo and cell models, analytical and computational theoretical models.
- Work with other members of the team, design, develop and refine experiments to obtain reliable data.
- Carry out research and development of experimental methods necessary to the aims of the project.
- Maintain an accurate and complete record of duties performed, including experiments.
- Provide help to other researchers in the same group and other groups with related research interests.
- As a member of staff, you will be encouraged to make ethical decisions in your role, embedding the University sustainability strategy into your working activities wherever possible.
- Carry out other duties, commensurate with the grade and remit of the post
Our diverse community of staff and students recognises the unique abilities, backgrounds, and beliefs of all. We foster a culture where everyone feels they belong and is respected. Even if your past experience doesn't match perfectly with this role's criteria, your contribution is valuable, and we encourage you to apply. Please ensure that you reference the application criteria in the application statement when you apply.
CriteriaEssential Or Desirable Stage(s) assessed at
A BSc Degree (or equivalent experience) in a relevant area
- Essential
Application
Experience of laboratory research methods and techniques - Essential
Interview / Application
Ability to hold a Home Office Personal Licence - Essential
Application
Ability to manage time and prioritise workload effectively with the ability to develop creating solutions to problems - Essential
Interview / Application
Ability to work as part of a team with varied skills, disciplinary background and experience and to maintain effective communication with team members and collaborators - Essential
Interview / Application
Attention to detail and a proven ability to keep accurate and reliable records - Essential
Interview / Application
Ability to work safely in a laboratory setting - Essential
Interview / Application
Experience of microscopy - Desirable
Interview / Application
Experience of laboratory management - Desirable
Interview / Application
Grade 5
Salary 5.1 £ 27,319
Work arrangement Full-time
Duration 1/10/2026 – 31/12/2027
Line manager Professor of Infection Biology
Direct reports N/A
Rig…
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