Lead Computational Biologist - Drug Discovery
South Africa
Listed on 2026-09-21
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Research/Development
Data Scientist, Research Scientist, Drug Discovery, AI Business & Operations
About the Role
Our client is seeking a highly experienced and visionary Lead Computational Biologist to spearhead their Drug Discovery initiatives in a fully remote capacity. This pivotal role involves leading a team of computational biologists and data scientists in the application of advanced computational techniques to identify and validate novel therapeutic targets. You will be instrumental in shaping the computational strategy, guiding project execution, and ensuring the effective integration of data-driven insights into the drug discovery pipeline.
This is an unparalleled opportunity for a scientific leader who is passionate about leveraging cutting-edge computational biology to accelerate the development of life-saving medicines, thriving in a collaborative, fully remote setting.
- Lead and mentor a team of computational biologists and data scientists focused on drug discovery research.
- Develop and implement computational strategies for target identification, validation, and hit-to-lead optimisation.
- Analyze complex biological data from various sources, including genomics, transcriptomics, proteomics, and chemical screening.
- Collaborate closely with medicinal chemists, biologists, and pharmacologists to integrate computational insights into project workflows.
- Oversee the development and maintenance of computational tools and databases to support drug discovery efforts.
- Communicate research progress and strategic recommendations to senior leadership and project teams.
- Ph.D. in Computational Biology, Bioinformatics, Computer Science, or a related quantitative field with a strong focus on drug discovery.
- A minimum of 8 years of progressive experience in computational biology, with demonstrated leadership experience.
- Extensive experience in applying computational methods to drug discovery, including target , virtual screening, and PK/PD modelling.
- Proficiency in programming languages such as Python and R, and expertise in relevant bioinformatics and cheminformatics tools.
- Experience with machine learning, AI, and big data analytics in a biological context.
- Excellent communication, interpersonal, and strategic thinking skills, essential for leading remote teams and initiatives.
- Exceptional salary and comprehensive bonus structure.
- Generous remote work benefits, including home office set-up and stipends.
- Full spectrum of health, dental, and vision insurance coverage.
- Significant opportunities for professional growth, innovation, and leadership development.
- A highly dynamic and collaborative remote research environment focused on impactful drug discovery.
- Flexible working hours promoting work-life integration.
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