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Principal Investigator - Drug Discovery

Remote / Online - Candidates ideally in
South Africa
Listing for: Placements24
Remote/Work from Home position
Listed on 2026-10-05
Job specializations:
  • Research/Development
    Research Scientist, Clinical Research
  • Healthcare
    Clinical Research
Job Description & How to Apply Below

Our client is actively seeking a visionary Principal Investigator to spearhead critical drug discovery initiatives from a remote setting. This senior role involves guiding a talented team of scientists in identifying and validating novel therapeutic targets for challenging diseases. You will be responsible for setting the scientific agenda, fostering a collaborative and innovative research culture, and ensuring the successful progression of projects through the discovery pipeline.

This position offers the unique advantage of a remote-first approach, allowing for flexibility while maintaining high scientific output and impact across the organization, contributing to significant breakthroughs in pharmaceutical research.

Key Responsibilities
  • Define and execute a strategic research plan for identifying and validating novel drug targets.
  • Lead and mentor a high-performing team of research scientists and technicians in a remote environment.
  • Oversee the design and implementation of high-throughput screening (HTS) campaigns and secondary validation assays.
  • Analyze complex biological data, interpret results, and make data-driven decisions to advance project goals.
  • Collaborate with external academic institutions and key opinion leaders to foster innovation and scientific exchange.
  • Author research reports, publications, and patent applications, representing the company's scientific achievements.
Requirements
  • Ph.D. in Pharmacology, Molecular Biology, Genetics, or a related life science discipline.
  • A minimum of 7 years of progressive experience in drug discovery, with a proven track record of leading successful research programs.
  • Demonstrated expertise in one or more therapeutic areas (e.g., oncology, immunology, neuroscience).
  • Strong understanding of drug discovery principles, including target identification, validation, and lead optimization.
  • Experience managing remote teams and utilizing virtual collaboration tools effectively.
  • Exceptional leadership, communication, and strategic thinking skills.
Benefits
  • Highly competitive salary with equity options and performance bonuses.
  • Comprehensive health, dental, and vision insurance plans.
  • Generous remote work stipend for home office setup and expenses.
  • Professional development opportunities, including conference attendance and leadership training.
  • A flexible and empowering work environment that prioritizes work-life balance and scientific excellence.
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