Senior Scientist​/Engineer: Transplantation, Biopreservation & Bioengineering

At Intertwine Associates, we live by a simple promise:
We show up ready to work. We partner with organizations across government, management, strategy, and technology to deliver operational efficiency and measurable impact. Our focus is on practical solutions, tailored frameworks, and innovation that drives meaningful results. Join a team where expertise meets execution, and where your work truly matters. Read more here:

Work in a dynamic, fast-paced environment as a Senior Scientist / Engineer supporting the Advanced Research Projects Agency for Health (ARPA-H) across a portfolio spanning transplantation, organ and tissue preservation, engineered tissues, organoids and microphysiological systems (MPS), and advanced therapeutic manufacturing. Collaborate with the ARPA-H Program Manager and team to effectuate bold research initiatives; support the development, funding, and management of new and existing R&D programs;

and help the agency accelerate better health outcomes for everyone. Provide direct technical support to R&D performer teams, Government Program Managers, and stakeholders across the health innovation ecosystem.

Bring deep technical expertise in transplantation and/or regenerative medicine, and apply it to emerging technologies in the context of clinical workflow, manufacturability, regulatory constraints, and real-world implementation. Provide technical and strategic support across programs related to tissue and organoid manufacturing, microphysiological systems and organ-on-chip platforms, tissue and organ preservation and biopreservation (including hypothermic and normothermic preservation, supercooling, cryopreservation, and vitrification), ex vivo organ perfusion and diagnostics, and other translational technologies relevant to organ and tissue recovery, preservation, and transplantation.

Evaluate technologies in the context of clinical and operational realities, including donor tissue and organ recovery, preservation logistics and cold-chain constraints, perfusion-enabled assessment and intervention, and transplant-center workflow. Conduct landscape analyses and technical diligence on emerging capabilities, vendors, performers, and scientific trends, and advise on the scientific plausibility, translational feasibility, manufacturability, and adoption potential of proposed approaches. Assess the commercialization pathway alongside the science: scale-up and manufacturability, quality systems and GMP considerations, regulatory strategy, reimbursement context, supply chain, and the clinical adoption barriers that determine whether a technology reaches patients.

Provide insight into how innovations may intersect with the broader transplant ecosystem, including organ procurement organizations, transplant centers, tissue banks, and applicable federal regulators and stakeholders. Review and assess technical proposals, performer submissions, milestones, deliverables, and program risks. Provide feedback, organize reviewer comments, and draft recommendations, project summaries, and presentation materials. Help identify subject-matter experts, potential performers, test and evaluation partners, and transition stakeholders across academia, industry, clinical practice, and government.

Assist in program management functions, including preparing for technical meetings, conducting site visits, consolidating performer progress, identifying schedule risks, and creating briefing materials. Maintain awareness of relevant scientific, clinical, regulatory, and market developments.

Strong client or customer engagement is required in this role. You will interface directly and continuously with the Government Program Manager, Mission Office leadership, performer teams, and external stakeholders across the transplant and bioengineering communities — and are expected to represent Intertwine Associates and the client with professionalism, responsiveness, and sound judgment at every touchpoint. This is a remote position with approximately 10-20% CONUS travel.

• Advanced degree in a relevant field:
  PhD in physiology, systems biology, bioengineering, tissue engineering, regenerative medicine, or a related discipline; or MD with significant experience in transplantation, organ preservation, transplant surgery, transplant medicine, or a closely related field.
• Demonstrated subject-matter expertise in one or more of the following: organ preservation, ex vivo organ…