Principal Scientist - Cheminformatics

Our client is looking for a visionary Principal Scientist in Cheminformatics to lead their computational chemistry efforts from a remote capacity. This senior role is critical for driving drug discovery through the application of advanced computational methods, machine learning, and data science to chemical and biological data. You will be responsible for developing and implementing novel informatics strategies, managing large chemical datasets, and collaborating with chemists and biologists to accelerate the identification and optimization of drug candidates.

This is an unparalleled opportunity for a leader in cheminformatics to shape the future of drug discovery in a flexible, remote-first setting.

• Lead the development and implementation of cheminformatics tools and platforms to support drug discovery programs.
• Apply machine learning, statistical modeling, and data mining techniques to analyze chemical structures and biological activity data.
• Design and develop novel algorithms for virtual screening, property prediction, and compound library design.
• Manage and curate large chemical and biological databases, ensuring data integrity and accessibility.
• Collaborate closely with medicinal chemists, biologists, and computational scientists to translate research needs into computational solutions.
• Mentor junior cheminformaticians and contribute to the strategic direction of computational drug discovery efforts.

• Ph.D. in Cheminformatics, Computational Chemistry, Computer Science, or a related quantitative field with a strong computational focus.
• Minimum of 8 years of experience in cheminformatics, with a proven track record of leadership and innovation in drug discovery.
• Extensive experience with cheminformatics toolkits (e.g., RDKit, KNIME) and programming languages (e.g., Python).
• Deep understanding of machine learning algorithms and their application to chemical data.
• Experience with database management and software development best practices.
• Exceptional problem-solving skills and the ability to communicate complex concepts effectively in a remote environment.

• Executive-level salary and significant bonus potential.
• Comprehensive benefits package including top-tier health, dental, and vision insurance.
• Generous paid time off and flexible remote work options.
• Substantial budget for professional development, conference attendance, and home office support.
• The chance to influence strategy and drive innovation at the forefront of computational drug discovery.