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Lead Computational Scientist

Remote / Online - Candidates ideally in
Mbombela, Mpumalanga, South Africa
Listing for: Placements24
Remote/Work from Home position
Listed on 2026-10-16
Job specializations:
  • Research/Development
    Research Scientist, Biotechnology, Biomedical Science, Drug Discovery
Job Description & How to Apply Below
Location: Mbombela

About the Role

Our client is seeking an innovative and experienced Lead Computational Scientist to join their advanced research team in Nelspruit . This role is instrumental in applying computational methodologies to solve complex biological problems, particularly in areas of drug discovery and development. You will lead a team of computational scientists, oversee the development of sophisticated modeling and simulation tools, and collaborate closely with experimental teams to accelerate research progress.

This hybrid position balances essential on-site collaboration in our modern facilities with the flexibility of remote work, fostering productivity and innovation.

Key Responsibilities
  • Lead the computational science group, providing scientific direction, mentorship, and project management.
  • Develop and implement advanced computational models, simulations, and data analysis strategies for biological systems.
  • Collaborate closely with experimental biologists, chemists, and pharmacologists to integrate computational findings into research programs.
  • Design and execute studies utilizing techniques such as molecular dynamics, structure-based drug design, and systems biology approaches.
  • Oversee the development and maintenance of computational infrastructure and software tools.
  • Present complex computational results and strategies to internal teams and external partners.
Requirements
  • Ph.D. in Computational Chemistry, Computational Biology, Physics, or a related quantitative field.
  • Minimum of 8 years of relevant experience in computational science, with a significant portion in drug discovery or a related industry.
  • Proven experience in leading and managing scientific teams.
  • Expertise in molecular modeling, cheminformatics, structural biology, and/or systems biology.
  • Strong programming skills in languages such as Python, C++, or Fortran, and experience with relevant scientific software packages.
Benefits
  • Highly competitive salary, bonus structure, and potential for equity.
  • Comprehensive medical, dental, and vision insurance.
  • Significant opportunities for career advancement and professional development in a growing field.
  • Access to world-class computational resources and cutting-edge research projects in Nelspruit .
  • A dynamic hybrid work environment that encourages collaboration and innovation.
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