Senior Computational Biologist - Drug Discovery
Bloemfontein, 9300, South Africa
Listed on 2026-10-20
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Research/Development
Data Scientist
Our client is a cutting-edge biotechnology firm dedicated to accelerating drug discovery through advanced computational approaches. We are seeking a highly skilled Senior Computational Biologist to join our fully remote team. This position is ideal for a candidate passionate about leveraging data science, machine learning, and bioinformatics to identify novel therapeutic targets and optimize drug candidates. You will play a crucial role in analyzing diverse biological datasets, including genomics, proteomics, and clinical trial data, to drive key decisions in our drug development pipeline.
The successful applicant will work collaboratively with a global team of scientists, programmers, and clinicians, contributing to a culture of innovation and scientific excellence, regardless of geographical location. This is a unique opportunity to significantly impact the future of medicine from the comfort of your home office, contributing to groundbreaking research with a remote-first mindset.
- Design, develop, and implement computational strategies for analyzing large-scale omics datasets (genomics, transcriptomics, proteomics, metabolomics).
- Apply machine learning and statistical modeling techniques to identify disease biomarkers, predict drug response, and uncover novel therapeutic targets.
- Develop and maintain robust bioinformatics pipelines for data processing, quality control, and analysis.
- Collaborate closely with experimental biologists, chemists, and pharmacologists to interpret results and guide research directions.
- Visualize complex biological data in an intuitive and informative manner for diverse audiences.
- Contribute to the development of predictive models for drug efficacy and toxicity.
- Stay abreast of the latest advancements in computational biology, bioinformatics, machine learning, and drug discovery methodologies.
- Author scientific manuscripts and present findings at international virtual conferences.
- Provide technical guidance and mentorship to junior computational biologists.
- Ph.D. in Computational Biology, Bioinformatics, Statistics, Computer Science, or a related quantitative field.
- Minimum of 7 years of experience in computational biology or bioinformatics, with a strong focus on drug discovery or related fields.
- Proven expertise in applying machine learning algorithms (e.g., deep learning, SVM, random forests) to biological data.
- Extensive experience with programming languages such as Python or R, including relevant scientific libraries (e.g., scikit-learn, Tensor Flow, PyTorch, Bioconductor).
- Proficiency in handling and analyzing large datasets, including experience with cloud computing platforms (AWS, GCP, Azure).
- Strong understanding of biological pathways, disease mechanisms, and drug development processes.
- Excellent analytical, problem-solving, and critical thinking skills.
- Superb written and verbal communication skills, with the ability to articulate complex computational concepts to non-computational scientists.
- Demonstrated ability to work effectively in a remote, collaborative team environment.
- As a fully remote position, we offer exceptional flexibility and work-life balance.
- The compensation package is highly competitive, including an annual performance bonus and equity options.
- Benefits include a comprehensive health insurance plan, a generous retirement savings contribution, and a home office stipend.
- We support continuous learning through online courses, virtual conferences, and access to cutting-edge computational resources.
- Join a forward-thinking company where your expertise in computational biology will drive innovation in drug discovery and make a tangible difference in patient lives, all from your remote workspace.
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