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Senior Computational Biologist - Drug Discovery

Remote / Online - Candidates ideally in
Bloemfontein, 9300, South Africa
Listing for: Placements24
Remote/Work from Home position
Listed on 2026-10-20
Job specializations:
  • Research/Development
    Data Scientist
Job Description & How to Apply Below
About the Role

Our client is a cutting-edge biotechnology firm dedicated to accelerating drug discovery through advanced computational approaches. We are seeking a highly skilled Senior Computational Biologist to join our fully remote team. This position is ideal for a candidate passionate about leveraging data science, machine learning, and bioinformatics to identify novel therapeutic targets and optimize drug candidates. You will play a crucial role in analyzing diverse biological datasets, including genomics, proteomics, and clinical trial data, to drive key decisions in our drug development pipeline.

The successful applicant will work collaboratively with a global team of scientists, programmers, and clinicians, contributing to a culture of innovation and scientific excellence, regardless of geographical location. This is a unique opportunity to significantly impact the future of medicine from the comfort of your home office, contributing to groundbreaking research with a remote-first mindset.

Key Responsibilities
  • Design, develop, and implement computational strategies for analyzing large-scale omics datasets (genomics, transcriptomics, proteomics, metabolomics).
  • Apply machine learning and statistical modeling techniques to identify disease biomarkers, predict drug response, and uncover novel therapeutic targets.
  • Develop and maintain robust bioinformatics pipelines for data processing, quality control, and analysis.
  • Collaborate closely with experimental biologists, chemists, and pharmacologists to interpret results and guide research directions.
  • Visualize complex biological data in an intuitive and informative manner for diverse audiences.
  • Contribute to the development of predictive models for drug efficacy and toxicity.
  • Stay abreast of the latest advancements in computational biology, bioinformatics, machine learning, and drug discovery methodologies.
  • Author scientific manuscripts and present findings at international virtual conferences.
  • Provide technical guidance and mentorship to junior computational biologists.
Requirements
  • Ph.D. in Computational Biology, Bioinformatics, Statistics, Computer Science, or a related quantitative field.
  • Minimum of 7 years of experience in computational biology or bioinformatics, with a strong focus on drug discovery or related fields.
  • Proven expertise in applying machine learning algorithms (e.g., deep learning, SVM, random forests) to biological data.
  • Extensive experience with programming languages such as Python or R, including relevant scientific libraries (e.g., scikit-learn, Tensor Flow, PyTorch, Bioconductor).
  • Proficiency in handling and analyzing large datasets, including experience with cloud computing platforms (AWS, GCP, Azure).
  • Strong understanding of biological pathways, disease mechanisms, and drug development processes.
  • Excellent analytical, problem-solving, and critical thinking skills.
  • Superb written and verbal communication skills, with the ability to articulate complex computational concepts to non-computational scientists.
  • Demonstrated ability to work effectively in a remote, collaborative team environment.
Benefits
  • As a fully remote position, we offer exceptional flexibility and work-life balance.
  • The compensation package is highly competitive, including an annual performance bonus and equity options.
  • Benefits include a comprehensive health insurance plan, a generous retirement savings contribution, and a home office stipend.
  • We support continuous learning through online courses, virtual conferences, and access to cutting-edge computational resources.
  • Join a forward-thinking company where your expertise in computational biology will drive innovation in drug discovery and make a tangible difference in patient lives, all from your remote workspace.
Position Requirements
10+ Years work experience
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