Associate Director, Generation Ophthalmology

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Job Area: R&D/Medical

Job Category:
Professionals

Job Site:
Remote

Location:

San Mateo, CA, US

Dompé is an Italian bio-pharmaceutical company that focuses on innovation, where a long tradition in the field of personal wellness goes hand-in-hand with a commitment to research and development to meet unsatisfied therapeutic needs.

Established in 1940 in Milan, Dompé has an industrial and biotech research hub in L’Aquila, in addition to branches in Europe (Barcelona, Berlin, Paris and Tirana). The company has approximately 900 employees. The US headquarters of Dompé are based in Boston (R&D) and in the San Francisco Bay Area (Commercial Operations).

The Associate Director, RWE Ophthalmology leads the design, execution, and dissemination of real-world evidence studies across Dompé's ophthalmology portfolio — spanning the marketed product and pipeline assets/diseases. Reporting to the Senior Director, RWE/HEOR, this individual partners closely with the Global Medical Indication Lead for Ophthalmology and Medical Communications to ensure ophthalmology-specific evidence needs are met with scientific rigor, strategic relevance, and a clear line of sight to how the evidence will be used in publications, HCP engagement, and, in partnership with HEOR colleagues, payor and formulary conversations.

The role requires both epidemiological expertise and enough ophthalmology therapeutic depth to shape study design, data source selection, and analytic approach so that resulting evidence holds up to clinical, scientific, and regulatory scrutiny.

• Build and maintain an ophthalmology RWE evidence generation roadmap spanning across all programs
• Identify and prioritize evidence gaps in partnership with the Global Medical Indication Lead for Ophthalmology, translating unmet evidence needs, including, natural history, disease burden, treatment patterns, comparative effectiveness, into a defensible study pipeline
• Select and evaluate real-world data sources appropriate to each evidence question, including claims databases, EHR networks, specialty registries, and pharmaceutical hub program data

• Design and manage observational studies, registries, and data analyses specific to ophthalmology, from protocol development through statistical analysis plan and final study report
• Oversee interpretation of RWE findings for ophthalmology assets, ensuring conclusions are appropriately caveated to data source limitations and confounding
• Lead data linkage and integration approaches across sources where appropriate, for example, linking claims data to hub program data for disease stage ascertainment
• Ensure studies meet scientific, ethical, and regulatory standards, including appropriate IRB/ethics oversight and data privacy compliance
• Manage project budgets, timelines, and vendor deliverables for assigned ophthalmology RWE studies

• Partner with the Global Medical Indication Lead for Ophthalmology to align evidence generation with medical strategy and the broader indication engagement plan
• Manage relationships with academic investigators, data vendors (e.g., Komodo Health, registry holders), and research partners, including scope definition, deliverable tracking, and data use agreements
• Translate study results into publications, congress presentations, and internal insight summaries in partnership with Medical Communications, ensuring findings reach both external scientific and internal strategic audiences
• Partner with HEOR colleagues to ensure RWE outputs are positioned to support value communication and…