Senior Metabolomics Assay Specialist

Job Title:

Senior Metabolomics Assay Specialist

Location: United Arab Emirates (Remote)

Employment Type: Full-Time

Work Arrangement: 100% Remote — Work From Home

Level: Senior

The Senior Metabolomics Assay Specialist provides advanced technical expertise in the evaluation, optimization, validation, and quality oversight of metabolomics assays used in biomedical research, pharmaceutical development, biotechnology, and clinical research. The role focuses on analytical method performance, metabolite identification, quantitative data quality, assay validation documentation, and interpretation of complex analytical datasets. Working fully remotely, the specialist collaborates with laboratory scientists, bioinformaticians, researchers, quality teams, and project stakeholders to ensure metabolomics methods are scientifically robust, reproducible, and appropriately documented.

• Review and assess targeted and untargeted metabolomics assay methodologies and analytical workflows.
• Provide technical guidance on assay design, method optimization, and analytical performance evaluation.
• Review data generated through liquid chromatography–mass spectrometry (LC-MS), gas chromatography–mass spectrometry (GC-MS), and other relevant analytical platforms.
• Evaluate assay sensitivity, specificity, selectivity, accuracy, precision, linearity, recovery, and reproducibility.
• Review calibration models, reference standards, quality-control samples, and analytical acceptance criteria.
• Assess sample preparation methodologies, including extraction procedures, derivatization strategies, and matrix-effect evaluations.
• Review metabolite identification, annotation, quantification, and confidence-level documentation.
• Evaluate analytical performance indicators such as detection limits, quantification limits, carryover, signal stability, and instrument drift.
• Assess batch performance, quality-control trends, analytical variability, and potential sources of measurement bias.
• Review assay validation, verification, transfer, and lifecycle management documentation.
• Support the evaluation of metabolomics data generated from biological matrices, including plasma, serum, urine, tissue, and cell-based samples.
• Review data-processing workflows, normalization approaches, statistical analysis outputs, and metabolite profiling reports.
• Collaborate with bioinformatics teams to assess data integrity, feature alignment, peak integration, and metabolite identification workflows.
• Investigate assay deviations, unexpected analytical results, outliers, and inconsistencies in laboratory-generated datasets.
• Recommend corrective and preventive actions to improve assay robustness, reproducibility, and data quality.
• Review method transfer packages and assess comparability between analytical platforms or laboratories.
• Support the development of standard operating procedures, analytical protocols, technical reports, and controlled documentation.
• Evaluate the suitability and traceability of reference materials, internal standards, and metabolite libraries.
• Contribute to analytical risk assessments and continuous improvement initiatives.
• Support internal audits, research quality reviews, and technical assessments relating to metabolomics assay performance.
• Monitor developments in metabolomics technologies, analytical chemistry, mass spectrometry, and relevant quality standards.

• Bachelor's degree in Analytical Chemistry, Biochemistry, Metabolomics, Biotechnology, Pharmaceutical Sciences, Molecular Biology, or a related discipline.
• A master's degree or PhD in Metabolomics, Analytical Chemistry, Biochemistry, or a related field is highly advantageous.
• Significant experience in metabolomics assay development,…