Senior Metabolomics Assay Specialist

Job Title:

Senior Metabolomics Assay Specialist

Location: United Arab Emirates (Remote)

Employment Type: Full-Time

Work Arrangement: 100% Remote — Work From Home

Level: Senior

We are seeking an experienced Senior Metabolomics Assay Specialist to provide technical oversight, analytical data review, and methodological support for metabolomics testing and research programs. This role focuses on evaluating assay performance, reviewing analytical workflows, interpreting metabolite profiling data, and supporting the quality and consistency of complex biochemical datasets. The successful candidate will bring expertise in metabolomics, analytical chemistry, mass spectrometry, chromatography, and laboratory quality systems, with the ability to collaborate effectively with research, laboratory, bioinformatics, and quality teams.

• Provide technical oversight of targeted and untargeted metabolomics assay programs across research, pharmaceutical, biotechnology, and related applications.
• Review metabolomics assay designs, analytical protocols, sample preparation strategies, and data acquisition plans.
• Evaluate analytical workflows involving liquid chromatography–mass spectrometry (LC-MS), gas chromatography–mass spectrometry (GC-MS), and other relevant platforms.
• Review nuclear magnetic resonance (NMR) spectroscopy data and workflows where applicable.
• Assess metabolite identification, annotation, quantification, and classification approaches.
• Review chromatographic separation, mass accuracy, retention time consistency, signal intensity, and analytical reproducibility.
• Evaluate calibration models, reference standards, internal standards, quality control samples, and batch acceptance criteria.
• Assess assay performance characteristics, including precision, accuracy, sensitivity, selectivity, linearity, recovery, and robustness.
• Review sample preparation and extraction protocols for their suitability in different biological matrices.
• Analyze metabolomics datasets to identify analytical trends, outliers, batch effects, and potential sources of technical variation.
• Review normalization, data transformation, missing-value handling, and quality control procedures used in metabolomics analysis.
• Coordinate with bioinformatics and statistical teams to support reliable interpretation of complex metabolite datasets.
• Evaluate analytical method validation, verification, transfer, and lifecycle documentation.
• Review deviations, unexpected analytical results, instrument performance issues, and laboratory investigation reports.
• Support the assessment of metabolite stability, degradation, storage conditions, and sample integrity.
• Coordinate technical discussions with research scientists, laboratory personnel, analytical development teams, and quality assurance stakeholders.
• Prepare technical review summaries, assay performance reports, analytical findings, and supporting documentation.
• Monitor developments in metabolomics technologies, analytical methods, data processing tools, and relevant scientific standards.
• Recommend improvements to assay design, analytical quality controls, data review practices, and reporting workflows.
• Support research and laboratory audits by reviewing technical records, analytical evidence, and controlled documentation.

• Master's degree or PhD in Metabolomics, Analytical Chemistry, Biochemistry, Molecular Biology, Pharmaceutical Sciences, Biotechnology, or a related discipline.
• Significant experience in metabolomics assay development, analytical chemistry, mass spectrometry, or biochemical research.
• Strong understanding of targeted and untargeted metabolomics methodologies.
• Experience with LC-MS and GC-MS analytical workflows, including chromatographic separation and mass spectrometric detection.
• Familiarity with NMR-based metabolomics and complementary analytical techniques is advantageous.
• Knowledge of metabolite extraction, sample preparation, derivatization, and biological matrix considerations.
• Experience reviewing calibration, quantification, reference standards, internal standards, and analytical quality control data.
• Understanding of assay validation principles, analytical performance characteristics, and method transfer requirements.
• Familiarity with metabolomics data processing, peak alignment, metabolite annotation, normalization, and statistical analysis.
• Experience with analytical software, laboratory information management systems, and scientific data platforms.
• Knowledge of…