Bioprocess Development Scientist

Our client, a leader in biotechnology and biopharmaceutical development, is seeking a talented Bioprocess Development Scientist to join their team in Mahikeng, North West . This role is critical for the development, optimization, and scale-up of mammalian cell culture processes for the production of biotherapeutic proteins. The scientist will be involved in hands-on laboratory work, experimental design, data analysis, and technology transfer.

This hybrid position combines essential laboratory time with flexible remote work options. You will contribute to the advancement of cutting-edge biologic therapies, working within a collaborative and innovative environment. Our client is dedicated to scientific rigor, quality, and bringing life-changing medicines to patients worldwide. This is an excellent opportunity for a motivated scientist looking to make a significant impact in the biopharmaceutical industry.

• Design and execute experiments for the development and optimization of mammalian cell culture processes (e.g., fed-batch, perfusion).
• Perform cell culture scale-up activities from benchtop to pilot scale.
• Utilize DOE (Design of Experiments) methodologies to efficiently optimize process parameters.
• Monitor and analyze critical process parameters (CPPs) and critical quality attributes (CQAs).
• Develop and implement robust analytical methods for process monitoring and product characterization.
• Troubleshoot process deviations and implement corrective actions.
• Prepare detailed reports, presentations, and technology transfer documents.
• Collaborate with cross-functional teams, including upstream development, downstream processing, analytical development, and manufacturing.
• Stay updated with the latest advancements in bioprocess technology and cell culture science.

• M.Sc. or Ph.D. in Chemical Engineering, Biochemical Engineering, Biotechnology, or a related discipline.
• Minimum of 3-5 years of hands-on experience in biopharmaceutical process development, specifically in mammalian cell culture.
• Strong understanding of cell biology, metabolism, and bioreactor operations.
• Experience with process optimization techniques, including DOE.
• Proficiency with common laboratory equipment and analytical techniques used in bioprocess development.
• Excellent data analysis, problem-solving, and critical thinking skills.
• Strong written and verbal communication skills.
• Ability to work effectively both independently and as part of a collaborative team in a hybrid setting.
• Experience with process scale-up and technology transfer is highly desirable.

• Competitive salary and annual bonus structure.
• Comprehensive medical and retirement benefits.
• Opportunities for professional development, training, and conference attendance.
• Hybrid work model offering flexibility.
• State-of-the-art laboratory facilities.
• Meaningful work contributing to the development of novel biotherapeutics.