Senior Cheminformatics Scientist

Our client, a pioneering biotechnology firm focused on drug discovery and development, is seeking a highly accomplished Senior Cheminformatics Scientist for a fully remote position. This role is central to leveraging computational approaches and data science techniques to accelerate the identification and optimization of novel therapeutic candidates. You will work at the forefront of computational chemistry and bioinformatics, developing and applying cutting‑edge tools and algorithms to analyze vast chemical and biological datasets.

The ideal candidate will possess a deep understanding of molecular modeling, cheminformatics databases, and machine learning applied to chemical structures. This is an exceptional opportunity to make a significant impact on drug discovery from the comfort of your home office, contributing to life‑saving therapies. You will collaborate closely with medicinal chemists, biologists, and computational scientists across distributed teams.

• Develop and implement advanced cheminformatics methods for drug discovery.
• Design, build, and maintain large‑scale chemical and biological databases.
• Apply machine learning and statistical techniques to analyze chemical structures, properties, and biological activity data.
• Develop predictive models for compound activity, ADMET properties, and synthetic feasibility.
• Collaborate with medicinal chemistry and biology teams to guide compound design and optimization efforts.
• Create and manage workflows for high‑throughput screening data analysis and hit‑to‑lead optimization.
• Develop and deploy cheminformatics software tools and platforms.
• Stay abreast of the latest advancements in cheminformatics, computational chemistry, and drug discovery.
• Communicate findings and contribute to research publications and presentations.

• Ph.D. in Cheminformatics, Computational Chemistry, Computer Science, or a related field with a strong computational focus.
• Minimum of 7 years of experience in cheminformatics or computational chemistry within the pharmaceutical or biotechnology industry.
• Proven expertise in chemical data representation (e.g., SMILES, molecular fingerprints), database management, and structure‑activity relationship (SAR) analysis.
• Strong programming skills in Python, R, or similar languages, with experience in relevant libraries (e.g., RDKit, Open Babel).
• Proficiency in applying machine learning techniques to chemical data.
• Experience with molecular modeling software and databases (e.g., Schrödinger, MOE, ChEMBL).
• Excellent analytical, problem‑solving, and communication skills.
• Ability to work independently and effectively in a remote team environment.
• Demonstrated ability to contribute to research publications and intellectual property.
• Must be legally authorized to work in South Africa .

Our client offers a competitive salary, comprehensive remote work benefits including health insurance coverage, a generous retirement plan, and performance‑based incentives. We provide a home office stipend and support for necessary equipment. Opportunities for continuous learning and professional development are prioritized, including access to online courses and virtual conferences. You will enjoy a flexible work schedule and a healthy work‑life balance.

Join a forward‑thinking company that values innovation and empowers its remote workforce to make significant contributions to the future of medicine.