District Manager, Sales

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

The District Manager is a field-based commercial leader responsible for building and leading a high-performing team of Clinical Account Specialists supporting the launch and ongoing growth of Ionis’ first wholly owned commercial product as its indication expands beyond Familial Chylomicronemia Syndrome to severe hypertriglyceridemia. The role reports to the Regional Executive Director.

• Own the district business plan and the achievement of quarterly and annual sales goals, with clear accountability for both collective district performance and individual territory execution.
• Translate regional and brand strategy into focused district priorities, territory objectives and account-level actions that reflect local market potential and barriers.
• Build a detailed view of the district's patient opportunity, HCP and account universe, referral networks, health systems and care pathways relevant to sHTG.
• Ensure resources and field time are directed toward the highest-value opportunities while maintaining sufficient reach and frequency across a broad customer base.
• Identify performance risks and market barriers early, communicate them clearly to regional leadership and implement specific recovery or acceleration plans.
• Maintain direct leadership engagement with strategically important health systems, IDNs, key accounts and senior customer stakeholders where appropriate.

• Set clear and consistent execution standards for prospecting, target coverage, customer activation, reach, frequency, call quality, follow-up and opportunity progression.
• Lead the CAS team to expand beyond established relationships, open new accounts and create momentum rather than waiting for patient identification or demand to emerge.
• Ensure CASs communicate the burden of disease and treatment opportunity credibly, create appropriate urgency and secure clear, compliant next actions with HCPs and office staff.
• Review territory and account plans for strategic focus, quality of insight, specificity of actions and evidence of measurable customer movement.
• Create a high-performance operating cadence that includes regular business reviews, opportunity assessment, field coaching, action tracking and follow-through.
• Share and scale effective practices across the district and region while adapting execution to…