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Principal Full-Stack Engineer — Remote; Security Clearance

Remote / Online - Candidates ideally in
Waldorf, Charles County, Maryland, 20601, USA
Listing for: X4 Life Sciences
Full Time, Remote/Work from Home position
Listed on 2026-11-05
Job specializations:
  • Software Development
    Full Stack Developer
Salary/Wage Range or Industry Benchmark: 180000 - 230000 USD Yearly USD 180000.00 230000.00 YEAR
Job Description & How to Apply Below
Position: Principal Full-Stack Engineer — Remote (Security Clearance)

X4 Life Sciences seeks a Principal Full Stack Engineer to lead the design and delivery of secure, scalable web applications and AI-integrated systems for a government department. You will own architecture decisions across front-end, back-end, cloud, and AI layers, and guide the team toward robust security and performance.

The role is primarily remote with occasional in-person attendance in the Washington DC area; some interview rounds may be conducted on-site.

The Principal Full-Stack Engineer — Remote (Security Clearance) role at X4 Life Sciences is now open for applications in MD, United States.

If your experience matches this role, we encourage you to apply.

All applications are reviewed carefully by our team.

The position is based in MD, United States.

This opportunity is part of our work in IT & Technology.

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