Postdoctoral Associate- Solt Lab

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- Solt Lab role at University of Florida

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- Solt Lab role at University of Florida

Job Description

The Solt lab at The Herbert Wertheim UF Scripps Institute of Biomedical Innovation and Technology, Department of Immunology and Microbiology, is seeking outstanding, creative, independent, and highly motivated postdocs. The Solt lab focuses on understanding and characterizing how nuclear receptors, a family of ligand-regulated transcription factors, influence T cell development, function, and chronic inflammatory diseases. Our goals are two-fold:
1) better understand how nuclear receptors function in immunity, and
2) develop and characterize small molecule ligands that modulate nuclear receptor function as tools to understand biology as well as potential therapeutic approaches. Specific to this application, this NIH-funded postdoctoral position will seek to understand how endogenous ligands regulate REV-ERB-specific transcriptional control of T H 17-mediated autoimmunity and chronic inflammation.

Classification Title

Postdoctoral Associate



Job Description

The Solt lab at The Herbert Wertheim UF Scripps Institute of Biomedical Innovation and Technology, Department of Immunology and Microbiology, is seeking outstanding, creative, independent, and highly motivated postdocs. The Solt lab focuses on understanding and characterizing how nuclear receptors, a family of ligand-regulated transcription factors, influence T cell development, function, and chronic inflammatory diseases. Our goals are two-fold:
1) better understand how nuclear receptors function in immunity, and
2) develop and characterize small molecule ligands that modulate nuclear receptor function as tools to understand biology as well as potential therapeutic approaches. Specific to this application, this NIH-funded postdoctoral position will seek to understand how endogenous ligands regulate REV-ERB-specific transcriptional control of T H 17-mediated autoimmunity and chronic inflammation.

This project is multidisciplinary, using a variety of techniques and approaches including immunology, mouse genetics, molecular biology techniques, and genomics. A successful candidate will contribute to all aspects of the project, including experimental design, analysis, and data interpretation. Please see description below for experience necessary for this position.

The successful candidate will assume a leadership position within the lab; set the tone for both scientific and scholarly excellence; drive forward complex, innovative and impactful projects; develop and write fellowship applications; participate in a variety of group and departmental seminar and journal club series, as well as national and international conferences. In return, the applicant will gain critical experience working in a fast-paced and dynamic group environment.

Dr. Solt is fully committed to supporting the career development of all her trainees with opportunities both in and outside of the lab and substantiative one-on-one interactions. She is keen to provide opportunities and support for women scientists who often leave the scientific workforce at this stage.

This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

Expected Salary: Commensurate with experience.



Minimum Requirements

The ideal candidate will have a Ph.D. (or MD/PhD) in biological sciences such as immunology, molecular biology, cell biology, or biochemistry, with a strong international publication record.



Preferred Qualifications

Preference will be given to candidates with:

• Expertise in immunology such as cell culture, flow cytometry, mouse genetics, in vivo

• Expertise in biochemistry, IP, WB, etc.
• Epigenetics/Genomics approaches:
  ChIP, ChIP-seq, ATAC-seq, RNA-seq, CUT&RUN, etc.
• Basic bioinformatic knowledge (R, Python, or other programming languages) or ability to

• Excellent oral communication and…