Research Associate Biochemistry

Prime objective of the ADS-R&D Bioconjugates Research function (Oss) is to provide best-in-class targeted delivery technologies, i.e. development of protein conjugation technologies, linkers and payloads. General focus is on cytotoxic ADCs, however other modalities to be employed in indications such as immuno‑oncology, targeted gene therapy, neuromuscular disease, neurodegeneration are also being pursued.

A Research Associate Biochemistry supports the ADS R&D agenda in the field of bioconjugation by contributing to the execution, and documentation of bioconjugation activities. In this role, the Research Associate performs a wide range of experimental tasks, ensuring high ‑ quality and reproducible results. They are proficient in applying the full spectrum of analytical techniques available in the laboratory and use these methods to characterize proteins and protein conjugates.

The Research Associate maintains accurate and comprehensive experimental records, actively contributes to project progression, and works closely with (senior) scientists.

An agile career and dynamic working culture.

An inclusive and ethical workplace.

Compensation programs that recognize high performance.

A variety of benefits dependent on role and location.

The full‑time annual base pay for this position in The Netherlands is expected to range between 41.250 EUR MIN and 57.750 EUR MAX. Initial salary placement within this range will be determined based on role ‑ related factors such as experience, qualifications, and expected contribution.

• Performs experiments as described in protocols.
• Performs enzymatic and chemical reactions on antibodies and other proteins. Reflects on the outcome of the experiments and discusses the results with their supervisor and proposes next steps.
• Purifies antibodies and other proteins using a FPLC system and laboratory techniques such as protein A chromatography, SEC and IEX.
• Characterizes antibodies and other proteins using laboratory techniques and equipment such as SDS‑PAGE, RP ‑ UPLC, SE‑UPLC, UPLC ‑ MS.
• Performs functional analyses including cell‑based assays (in vitro cytotoxicity, reporter cell lines) and ELISA‑based assays.
• Maintains high experimental standards through strong attention to detail.
• Documents procedures, results and conclusions timely and accurately in Electronic Lab Notebooks (ELN). Review and approve ELN experiments from colleagues to guarantee accuracy and consistency.
• Handles hazardous and toxic materials responsibly while ensuring safe and compliant laboratory practices and adheres to safety and compliance guidelines.
• Supports additional tasks (maintaining equipment, coordinate maintenance with suppliers, manage inventory, ordering) as assigned and contributes to an efficient laboratory environment.
• Provides weekly updates in the Biochemistry Team meeting.

• BSc/MSc degree in biochemistry, molecular biology, chemical biology or related field
• Possesses knowledge on bioconjugation, protein purification and protein characterization
• Has experience with protein purification techniques (ProtA, SEC, IEX) and analytical techniques (SDS‑PAGE, RP‑UPLC, SE‑UPLC, UPLC ‑ MS)
• Shows strong commitment to laboratory work and task delivery
• Communicates clearly in English both verbal and in writing
• Acts as a strong team‑player and demonstrates excellent time‑management skills
• Has a responsible, conscientious, and sociable character