Industry placement | Nonclinical safety
Listed on 2025-12-04
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Research/Development
Research Scientist, Clinical Research
Year in industry placement | Nonclinical safety
Location:
Oxford, UK
Department Biology Pipeline
Summary We are seeking a motivated student to join our Nonclinical Safety Team to work on engineering cell models to evaluate novel bispecific molecules. You will use state‑of‑the‑art genetic engineering tools to perturb specific genes or introduce synthetic molecular circuits into mammalian cells and generate robust in vitro models for pharmacological testing. This role offers hands‑on training in advanced molecular biology and cell biology techniques directly applied to the discovery and assessment of novel Immuno-engagers.
Key Responsibilities- Genetic Engineering and Cell Line Development:
In silico design of synthetic nucleic acid sequences (e.g., sgRNAs, plasmids); generation and propagation of plasmid stocks, molecular cloning; generate, characterize, and maintain engineered cell lines for use in preclinical assays; validate genetic perturbations at the DNA, RNA, and/or protein level (e.g., PCR/qPCR, western blot, flow cytometry, immunofluorescence, Next Generation Sequencing); apply engineered cell models to assess the pharmacological effects of bispecific molecules;
perform cell based assays (e.g. co-culture with immune cells, T cell activation assays, killing assays, cytokine release assays) to study pharmacological responses to gene perturbation. - Data Analysis and Documentation:
Analyze data, generate summary reports, interpret results; maintain detailed electronic laboratory notebooks, protocols, and records in accordance with company policies and industry standards; present results in internal meetings and contribute to internal reports or presentations. - Laboratory Operations:
Perform routine laboratory maintenance tasks; follow all safety, biosafety, and quality guidelines. - Education and
Qualifications:
Candidates need to be undertaking (currently in second year and looking for a year in industry) a BSc. in Biological or Biomedical Sciences, Biochemistry, Immunology, Pharmacy, Pharmacology, or related disciplines.
- Paid placement with 25 days of annual leave (pro rata), pension scheme eligibility, and access to the Sports and Social Club with subsidized events.
- This is a full‑time position based at our Abingdon, Oxfordshire office and contracted through a third party.
The Final date to receive applications is 09 January 2026, with phone interviews starting shortly after. Shortlisted candidates will be invited to an in‑person Assessment Centre on 23–26 February 2026. Placements are expected to begin on 7 September 2026. Please only apply if you are currently pursuing a degree with a placement year (sandwich year). If you are not available on all the above dates, we won’t be able to proceed with your application.
Please apply with your CV and a cover letter (combined in one document) stating your main areas of interest.
Immunocore (NASDAQ: IMCR) is a pioneering, commercial‑stage T cell receptor biotechnology company focused on developing transformative medicines addressing unmet patient needs in oncology, infectious diseases, and autoimmune disease. We are committed to STRIDE values:
Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship. Immunocore is an equal opportunity employer and we encourage applications from individuals of all backgrounds.
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Equality and diversity information:
Immunocore is an equal opportunity employer. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.
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