Post Doc, Wellcome SynHG - Generative Biology Institute

The Ellison Institute of Technology (EIT) tackles humanity's greatest challenges by turning science and technology into impactful global solutions. Focused on areas like health, food security, sustainable agriculture, climate change, clean energy, and robotics in an era of artificial intelligence. EIT blends groundbreaking research with practical applications to deliver lasting results.

A cornerstone of EIT mission is its upcoming 300,000-square-foot research facility at the Oxford Science Park, set to open in 2027. This cutting-edge campus will feature advanced labs, an oncology and preventative care clinic, and collaborative spaces to strengthen its partnership with the University of Oxford. It will also host the Ellison Scholars, driving innovation for societal benefit.

The Generative Biology Institute (GBI) at the Ellison Institute of Technology (EIT) aims to overcome two major challenges in making biology engineerable:
1) the ability to precisely synthesize entire genomes, and
2) understanding which DNA sequences will create biological systems that perform desired functions. Solving these challenges will unlock the potential of biology for transformative solutions in health, sustainability, agriculture, and more. GBI will house 30 groups and over 300 researchers, supported by cutting-edge facilities and sustained funding to address global challenges and advance biology engineering.

EIT fosters a culture of collaboration, innovation, and resilience, valuing diverse expertise to drive sustainable solutions to humanity's enduring challenges.

Wellcome SynHG

Professor Chin is the lead Principal Investigator on the Wellcome Synthetic Human Genome (SynHG) project, for which research will be conducted at GBI in Oxford. The aim of the five-year multi-centre project (supported by £10m of funding) is to develop the foundational and scalable tools, technology and methods needed to synthesise large sections of human genomes/chromosomes. Through programmable synthesis of genetic material the aim is to unlock a deeper understanding of life, leading to potential acceleration of the development of safe, targeted, cell-based therapies, and opening entire new fields of research in human health.

The project aims to achieve reliable genome design and synthesis - engineering cells to have specific functions - which will be a major milestone in modern biology. A dedicated social science program will support the research.

Job Summary:

EIT is seeking a highly motivatedPostdoctoral Researcher to join the Wellcome SynHG team based  successful candidate will contribute to the research aims of the grant, working collaboratively and independently to design and conduct experiments, develop new techniques and approaches, and drive forward the scientific agenda. The Postdoctoral Researcher will play a key role in supporting lab development, and contributing to publications, reports, and presentations.

Key Responsibilities:

• Design and execute experiments aligned with the aims of the grant, including developing novel methodologies or adapting existing techniques to new applications
• Analyse complex datasets using appropriate computational and statistical tools, and interpret results in the context of the broader research objectives
• Contribute intellectually to the direction of the project by identifying opportunities to innovate, troubleshoot experimental challenges, and refine research questions
• Prepare written materials including scientific publications, reports, presentations, and protocols
• Collaborate with other group members and external partners to ensure progress across complementary work streams
• Contribute to the development of the lab's research infrastructure and capabilities
• Mentor and support junior team members, including Research Assistants
• Stay up to date with relevant scientific literature and bring emerging technologies and approaches into the lab
• Present findings at internal and external meetings and conferences
• Undertake other duties in support of the research group as requested by the Group Leader

Essential & Desirable Knowledge, Skills and Experience:

• A PhD (or equivalent) in a relevant scientific discipline (e.g.…