Research Senior Scientist – Engager Evaluation

Location of role
:
Oxford, UK

Department
:
Biology Pipeline

• Individual is expected to be a highly experienced scientist with a strong working knowledge of immuno‑oncology and the drug‑development process. They will be confident in designing and conducting experiments that enable the advancement of the Company’s pipeline through the functional validation of our ImmTAX molecules.
• Independently plan, design, conduct and analyse biological assays to support the functional assessment of ImmTAX™: molecule screening through to preclinical packages in accordance with set timelines.
• Proactively contribute to internal project / programme team meetings. Generate and communicate knowledge and data packages to solve complex problems and help inform go / no‑go decisions.
• Understand and align with strategy within the therapeutic area and Research.
• Collaborate with colleagues to build a deep knowledge around targets and technologies of strategic interest to Immunocore.
• Introduce new techniques/approaches that improve preclinical workflows.
• Establish and support collaborations with both internal and external partners.
• Keep up to date with scientific literature and the latest developments in applicable research fields.
• Contribute to peer reviewed publications and patents.
• Contribute to internal and external conferences.
• Provide technical training and mentorship to support and empower team members.
• Contribute to the operational running and maintenance of laboratories and equipment.

Experience & knowledge

• Strong working knowledge and understanding of immunology and cell biology.
• Prior experience of testing potential therapeutic molecules in relevant systems.
• Highly experienced in a broad range of immunoassay techniques, including isolation of primary human immune cells and proficiency in functional assays and endpoints (measuring proliferation and cytokines, flow cytometry, ELISA etc.).

Experience With Culturing Human Primary Cells From Patient Samples

• Capable in the genetic modification of cell lines and/or primary human immune cells. Evidence of using GM in vitro models to answer biological hypotheses.

Excellent written & oral communication skills

• Attention to Communication:
  Ensuring information and work is passed on correctly and in a timely way to those who depend on it.
• Written & Oral Communication:
  Writing and speaking clearly to share thoughts and information concisely and appropriately.
• Diagnostic Information Gathering:
  Identifying the information required to clarify a situation, asking questions when required.
• Results Orientated:
  Focusing on desired results, seeking help and support to overcome obstacles in a timely manner.
• Thoroughness:
  Ensuring work and information provided is complete, carefully checking and seeking additional support to help achieve this if needed.
• Managing Self Performance:
  Works to specific and measurable goals, seeking support and advice when dealing with unfamiliar or new issues.
• Analytical Thinking:
  Tackling day‑to‑day problems using a logical and systematic approach, identifying discrepancies and inconsistencies.

• PhD or equivalent in Immunology, Pharmacology, Oncology, Molecular cell biology or similar discipline.
• 3+ years’ experience of post‑doctoral research in an academic or industrial setting.
• Or, MSc degree or BSc degree with role‑specific equivalent research or industrial experience.

Immunocore (NASDAQ: IMCR) is a pioneering, commercial‑stage T cell receptor biotechnology company whose purpose is to develop and commercialise a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.

Focused on delivering first‑in‑class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision…