Senior Research Associate, Clinical Biomarker Laboratory, Flow Cytometry

Position: (Fixed Term) Senior Research Associate, Clinical Biomarker Laboratory, Flow Cytometry
## (Fixed Term) Senior Research Associate, Clinical Biomarker Laboratory, Flow Cytometry Apply locations:
Oxford - England:
Clinical Development time type:
Full time posted on:
Posted Todayjob requisition :
R19237
*
* The Role:

** Joining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients.

Moderna is establishing a leading research, development, and manufacturing facility at Harwell to support onshore mRNA vaccine production for respiratory diseases in the UK.This long term investment will create skilled jobs and strengthen collaboration with academic, NHS, and government partners. We welcome experts ready to help expand access to life saving vaccines.

This is an exciting opportunity for a highly motivated Senior Research Associate to join Moderna’s Clinical Flow Cytometry group in Harwell, Oxfordshire on a 1-year fixed term contract. Operating as an individual contributor within a collaborative scientific environment, you will serve as a technical expert in the generation of high parameter flow cytometry data under GCLP guidelines to support clinical programs across multiple therapeutic areas across the UK.You

will play a critical role in generating high quality clinical trial data through the development, validation, and execution of advanced cell-based flow cytometry assays. Working closely with scientists and laboratory associates, you will help drive key clinical decisions through robust immunophenotyping, functional immune profiling, and complex assay execution using cutting edge spectral flow technologies and digital laboratory systems.

This role offers the opportunity to work at the forefront of translational immunology and mRNA medicine, leveraging advanced laboratory technologies, digital workflows, and emerging analytical tools while contributing to innovative clinical programs with global patient impact.
** Here's

What You’ll Do:

*** Execute clinical sample testing under GCLP guidelines to support Moderna clinical programs across multiple therapeutic areas.
* Conduct functional profiling of immune responses on clinical trial samples using validated flow cytometry assays.
* Perform high parameter immunophenotyping on PBMC and whole blood samples with strong attention to assay quality and reproducibility.
* Apply high parameter spectral flow cytometry approaches to generate clinically meaningful immune monitoring data.
* Participate in the development and fit-for-purpose validation of complex cell-based flow cytometry assays.
* Execute clinical sample testing activities in accordance with established protocols, technical procedures, and documentation requirements.
* Ensure strict adherence to GCLP standards, assay rigor, data integrity expectations, and reproducibility requirements.
* Deliver high quality data within defined timelines while maintaining alignment with current industry standards for quality and compliance.
* Identify, troubleshoot, and escalate assay or quality issues as appropriate to maintain operational excellence.
* Process PBMC samples and qualify cryopreserved PBMCs received from clinical and vendor sites to ensure optimal sample integrity and performance.
* Support end-to-end experimental workflows including sample preparation, staining, instrument acquisition, and downstream data analysis.
* Analyze complex flow cytometry datasets using FCS Express software with a high level of technical accuracy.
* Document experimental procedures and testing activities using LES and LIMS platforms to maintain compliant digital laboratory records.
* Collaborate closely with scientists and laboratory colleagues to execute experiments efficiently and effectively.
* Contribute to continuous improvement initiatives focused on enhancing laboratory accuracy, workflow efficiency, and assay robustness.
* Partner with the team to feasibility test and implement emerging laboratory techniques and innovative technologies, including opportunities to work alongside advanced digital and AI-enabled scientific tools.
* Support laboratory operations through general housekeeping and shared…