Research Assistant in bacterial genome dynamics

About the role

We are seeking a talented individual to join the lab of Professor Stephan Uphoff as a Research Assistant on an interdisciplinary project investigating genome dynamics in the human pathogen Acinetobacter baumannii. The project is a collaboration with the labs of David Grainer (Birmingham) and Edze Westra (Exeter), funded by a Wellcome Trust Discovery Award. Research in this lab addresses the molecular mechanisms of DNA repair and mutagenesis in bacteria, and how these mechanisms are regulated when bacteria encounter different types of stress conditions.

This project will build on our developments of microscopy techniques to visualise processes at the single-molecule and single-cell level.

The post holder will have a Master level qualification in Biochemistry (or related discipline) and experience in performing original lab-based research, which can be through their degree or relevant work experience. We are looking for a candidate with hands‑on knowledge in molecular biology, bacterial genetics, working with pathogenic bacteria, and single‑molecule fluorescence microscopy. You will be working together with experienced lab members to support the technical aims of the project.

The lab is equipped with state‑of‑the‑art instrumentation embedded in a modern laboratory environment for microbiology & molecular biology. We have access to a large range of outstanding facilities at the Department of Biochemistry and the wider University of Oxford.

This full‑time fixed‑term post is funded by the Wellcome Trust for up to 1 year in the first instance.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

You will hold a master’s degree in Biochemistry or a related subject and demonstrate a strong passion for research, with enthusiasm for working as part of a team on an interdisciplinary project to solve fundamental biological questions. You will have expertise in cell culture, molecular biology, and the genetic manipulation of bacteria, alongside experience in single‑molecule fluorescence microscopy. You will have experience in performing and optimising complex laboratory and analytical methods and be able to effectively manage your own research and administrative activities.

Excellent communication skills are essential, including the ability to prepare publishable written material, present research findings at conferences, and represent the research group erience working with pathogenic bacteria would be an advantage.

Your happiness and wellbeing at work matters to us, so we offer a range of family‑friendly and financial benefits including:

• Excellent contributory pension scheme
• 38 days annual leave
• A comprehensive range of childcare services
• Family leave schemes
• Membership to a variety of social and sports clubs
• Discounted bus travel and Season Ticket travel loans

The University also runs an enormous amount of social groups and sports clubs for those looking for more than just a great place to work.

Applications for this vacancy are to be made online via  and Vacancy . You will be required to upload your curriculum vitae and a supporting statement, setting out how you meet the selection criteria for the post, using examples of your skills and experience. Clickhere for information and advice on writing an effective Supporting Statement. As part of your application, you will be asked to provide details of two referees and indicate whether we can contact them now.

For further details, please refer to the

How to apply

section of the job description. Any further enquiries may be directed to  .

The closing date for applications is 12.00 noon on Monday 6 July 2026. Only applications received before this time can be considered. Interviews for shortlisted candidates to be held as soon as possible thereafter.

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