Research Facility Scientist

Location: John Radcliffe Hospital, Headington, Oxford OX3 9DS

As Research Facility Scientist, you will contribute to all aspects of model generation and validation. Responsibilities will include:

• Design and construction of molecular reagents and targeting constructs
• Mammalian cell culture and genome editing
• Molecular genetic validation of edited lines
• Embryo manipulation and transgenic model production
• Cryopreservation (embryo and sperm freezing)
• Rederivation of mouse lines via IVF and embryo transfer
• Management of mouse colonies

You will work closely with researchers across the Institute to deliver high‑quality, reproducible model systems that underpin innovative scientific programmes.

You will hold a degree in Biological Sciences (or a closely related discipline) and have relevant laboratory experience. Essential experience required includes:

• Molecular biology techniques
• CRISPR genome editing
• Mammalian cell culture
• Transgenic model generation
• Mouse colony management
• Cryopreservation and rederivation techniques

You will also demonstrate excellent interpersonal and communication skills, strong organisational ability, and a clear commitment to supporting high‑quality scientific research.

This is a full‑time (37.5 hours per week) fixed‑term position for 3 years.

£39,424 to £47,779 per annum. Grade 7