Postdoctoral Research Scientist in Correlative Imaging of HIV-Transcription and Latency in CD

Position Overview

Postdoctoral Research Scientist in Correlative Imaging of HIV-1 Transcription and Latency in CD4⁺ T Cells

Division of Structural Biology, Building for Genomic Medicine, Roosevelt Drive, Oxford, OX3 7BN

• Manage the day‑to‑day execution of the Correlative Imaging project, including design and implementation of molecular biology, protein biochemistry, CRISPR‑based cell modification, and cellular imaging strategies.
• Lead structural studies using SPA cryoEM, cryoET, and related techniques to characterize HIV persistence.
• Supervise students and collaborate with partner organisations and research groups.
• Contribute to programme development and prepare for subsequent research phases.

• PhD/DPhil (or close to completion) in structural and functional studies of viral infections, or a closely related field.
• Demonstrable experience in molecular biology, protein biochemistry, and cryoEM structure determination.
• Background in retroviruses and in‑situ structural biology, including cryoET subtomogram averaging.
• Strong decision‑making, problem‑solving, and project planning skills.
• Ability to lead research projects and support junior researchers.

• Full‑time, fixed‑term contract until 31 May 2028, funded by NIH/NIAID.
• Salary (£):
  Research Grade 7 – £39,424 – £43,984 per annum, inclusive of a pensionable Oxford University weighting of £1,730 per year (pro‑rata).
• Key reference:
  186683