Senior Screening Scientist

Your impact starts here As Senior Screening Scientist, you’ll play a leading role in the identification, validation and maturation of novel therapeutic targets across Novo Nordisk's research portfolio. This is an exciting opportunity for an experienced scientist to combine deep expertise in functional genomics, CRISPR technologies, advanced automated screening platforms and human biology to generate transformative insights that drive the next generation of therapies.

What you’ll bring You are an accomplished scientist with a proven track record of applying functional genomics technologies to solve complex biological problems  combine scientific depth with strategic thinking, strong collaboration skills and a passion for translating cutting-edge science into therapeutic opportunities.

To succeed in this role, you will have:

A PhD in Functional Genomics, Molecular Biology, Cell Biology, Genetics or a related scientific discipline, with significant industrial and/or postdoctoral experience.

Typically, 5+ years of experience applying functional genomics approaches in pharmaceutical, biotechnology or academic research environments.

Deep expertise in CRISPR-based functional genomics, including gene editing, gene perturbation and screening technologies.

Proven experience designing, executing and interpreting functional genomics studies using physiologically relevant cellular systems.

Experience leading medium- to high-throughput screening campaigns and translating results into project-driving biological insights.

Experience developing assay strategies that are compatible with laboratory automation and scalable screening workflows.

Strong knowledge of experimental design, statistics and data analysis, including the interpretation of large and complex biological datasets.

A track record of scientific innovation demonstrated through impactful publications, platform development, patents or significant project contributions.

Experience leading scientific initiatives, influencing research direction and contributing to multidisciplinary project teams.

Experience with laboratory automation, advanced screening technologies and high-content phenotypic approaches.

Ability to mentor and develop scientists while fostering a collaborative and high-performing team environment.

Excellent communication and stakeholder management skills, with the ability to present complex scientific concepts to diverse audiences.

What you’ll doAs Senior Screening Scientist, you will lead the design and application of functional genomics strategies to support target identification, validation and maturation. Working across multidisciplinary teams, you will combine innovative experimental approaches, advanced screening technologies and biological insight to address complex research questions and inform key portfolio decisions.  In this role, you will provide scientific leadership, influence research strategy, champion new technologies and mentor colleagues while delivering high-impact science in a collaborative research environment.

Your responsibilities will include:

Leading the design and implementation of functional genomics strategies using siRNA, CRISPR-based perturbation technologies, gene editing and advanced human cellular models to identify and validate novel therapeutic targets.

Providing scientific leadership in the development of automation-compatible assay workflows by partnering with Automation Scientists to ensure assays are robust, scalable and ready for deployment on automated screening platforms.

Designing and leading medium-throughput screening campaigns, ensuring robust experimental design, data quality and scientific reproducibility.

Driving the adoption of emerging functional genomics, screening and automation…