Senior Postdoctoral Researcher in Computational Biology

Senior Postdoctoral Researcher in Computational Biology

Oxford Vaccine Group, Centre for Clinical Vaccinology and Tropical Medicine/ Institute of Developmental and Regenerative Medicine, Headington, Oxford

We have an exciting opportunity for a highly motivated Senior Postdoctoral Research in Computational Biology to join the Oxford Vaccine Group (OVG). Working within a pioneering multidisciplinary research programme, you will contribute to the development of innovative computational and systems biology approaches to uncover the mechanisms underlying protection against infectious diseases and vaccine-induced immunity. By integrating complex datasets generated through vaccine studies and controlled human infection models (CHIMs), the programme aims to accelerate vaccine discovery through the application of systems immunology and artificial intelligence.

The postholder will lead a defined area of computational biology and bioinformatics research within the programme, developing original research questions and applying advanced computational approaches to analyse and integrate complex clinical, immunological and multi-omic datasets generated through controlled human infection, vaccination and related studies. They will develop and implement new computational and bioinformatic methodologies, including reproducible analytical workflows, statistical and predictive approaches, to investigate immune responses and biological mechanisms associated with protection against infection and vaccination.

Working closely with immunologists, clinicians, microbiologists, statisticians, data scientists and AI specialists, the postholder will provide computational leadership within multidisciplinary research projects, integrating computational and experimental findings to address the programme's scientific objectives. They will have substantial scope for scientific independence, including generating original research ideas, identifying new research opportunities arising from programme datasets and contributing to the development of the programme's computational biology research strategy.

The postholder will also provide scientific guidance and supervision to junior researchers and students, contribute to collaborative funding applications, and lead and contribute substantially to the dissemination of research through high-quality peer-reviewed publications, seminars and presentations at scientific conferences

You will be working in a growing department within the Medical Sciences Division. The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. The Oxford Vaccine Group is a world-leading academic research group conducting clinical and translational studies to advance vaccine development working with a diverse portfolio funded by industry, government and charitable organisations.

This position is offered full-time on a fixed-term contract initially for 3 years with the possibility to extend provided further external funding is available.

The Department of Paediatrics has been honoured with the Athena Swan Gold award, a national gender equality charter, recognising the Department's innovative policies and practices. We are committed to the professional development of our staff by providing up to ten paid days annually for skill enhancement and allowing applications for additional training funding. By joining us, you will have the opportunity to contribute to a forward-thinking department.

We welcome new staff with ideas who are willing to shape the future of the department that thinks…