Medical Scientist

Are you a highly accomplished Immunologist with a track record of leading scientific teams and driving biologics discovery programmes in autoimmune and inflammatory diseases? Proclinical is recruiting for a Principal Scientist, this position will oversee breakthrough work in inflammation and immunology. You'll play a central role in shaping therapeutic approaches, developing next-generation biologic therapies, mentoring talented scientists, and advancing programs from target identification to preclinical development.

Working at the forefront of immunology research, you will lead and support multidisciplinary programmes spanning target identification, pharmacology, translational research and therapeutic antibody development. You will combine hands-on scientific expertise with leadership, helping to advance novel biologic therapies from early discovery through preclinical development.

Responsibilities:

Lead and mentor a team of laboratory-based scientists, supporting both scientific delivery and career development

Design, oversee and interpret complex in vitro and in vivo pharmacology studies

Drive the development of novel therapeutic strategies within autoimmune and inflammatory disease programmes

Design and optimise immune-based assays to support target validation and antibody discovery

Collaborate closely with experts across immunology, translational medicine, protein engineering, biomarkers and clinical development

Work with CRO partners to coordinate efficacy and pharmacology studies

Develop and implement endpoint and mechanism-of-action studies, including ex vivo immune profiling

Identify project risks, influence programme strategy and support key decision-making discussions

Contribute to scientific publications, patents, regulatory documentation and due diligence activities

Represent research programmes through conference presentations and external scientific collaborations

Key Skills and Requirements:

PhD in Immunology, Life Sciences or a related discipline

Minimum 5 years' experience within immunology, inflammation research or biologics drug discovery

Strong understanding of autoimmune disease biology and immune system mechanisms

Proven experience leading scientific projects and mentoring research teams

Expertise across in vitro pharmacology, assay development and immune profiling

Experience supporting biologics, antibody or therapeutic development programmes

Strong publication record with peer-reviewed scientific contributions

Excellent communication, stakeholder management and leadership skills

Biotechnology or pharmaceutical industry experience

In vivo pharmacology programme leadership

Translational research and target validation experience

Experience working with CROs and external research partners

Contribution to IND-enabling studies, patent applications or due diligence activities

Exposure to strategic portfolio or pipeline decision-making

If you are having difficulty in applying or if you have any questions, please contact Neil Walton at  you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page.

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