Associate Director, Disease and Target Biology

Category:
Data & AI

Location:

Oxford, South East, GB

Job title: Associate Director, Disease and Target Biology

Department: Disease and Target Biology;
Data Science

Location: Oxford, United Kingdom

Lead a front-line scientific team that exploitshuman genetics, multi-omics , and patient data to deepen disease understanding and identify new opportunities for target discovery. As Associate Director, Disease and Target Biology, you will leverage your scientific and people leadership expertise to drive target discovery campaigns with our Therapy Areas and translate complex evidence into clear decisions. You and your team will work with the TAs to define the biological evidence needed to move targets and programmes forward across Type 2 Diabetes, Obesity, Cardiovascular, and Renal disease.

You are an experienced scientific leader who can move confidently between detailed analysis, team development, and strategic decision-making. You bring strong expertise in human genetics and computational biology, along with the ability to explain complex evidence clearly to scientific and senior stakeholders.

• A PhD in human genetics, computational biology, genetic epidemiology, or a related discipline, together with substantial post-PhD experience.
• Experience combining genetics and omics with cohort or patient data to identify and stratify patient subgroups; and demonstrated experience applying this to actionable disease understanding and target discovery / validation.
• At least 5 years of leadership experience in drug/target discovery, with pharmaceutical, biomedical, or techbio industry experience strongly preferred.
• Experience leading and developing scientific teams, ideally across multiple locations, and comfortable remaining hands-on technically.
• Strong communication and stakeholder-management skills, including the ability to influence therapeutic area partners and senior leaders.

• Experience managing teams across sites or time zones .
• Direct e xperience in metabolic, cardiovascular , or renal disease.
• Familiarity with artificial intelligence and machine-learning approaches applied to biological and clinical data.
• An understanding of the drug discovery and development value chain.
• A strong publication record and standing in the external scientific community would also be valuable.

• Lead and develop a team of approximately seven scientists based across the UK and Denmark, taking responsibility for recruitment, performance, development, well-being and an effective cross-site working environment.
• Use human genetics, multi-omics and cohort or patient data to identify and stratify patient subgroups; applying results in pursuit of better disease understanding and testable hypotheses for target discovery.
• Co-lead scientific campaigns with therapeutic area teams, defining the biological evidence required to support or challenge hypotheses and enable programme decisions.
• Set the team’s scientific and operational direction in partnership with Data Science leaders and colleagues across AI & Digital Innovation and Global Research.
• Guide the application of artificial intelligence and machine learning in disease biology, work with engineering teams on deployment, and provide scientific leadership for academic and biotechnology collaborations.

You will join the Disease and Target Biology team within ADI Data Science and report to Robert Kitchen. The role leads approximately seven direct reports with varying levels of seniority and specialist expertise across the UK and Denmark.

Your closest partners will include Therapy Area colleagues working in Type 2…