Organic Chemist - Synthesis Specialist
Listed on 2026-10-17
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Research/Development
Research Scientist, Drug Discovery, Pharmaceutical Science/ Research, Biotechnology -
Science
Research Scientist, Drug Discovery, Pharmaceutical Science/ Research, Biotechnology
Our client, a prominent research and development organization, is seeking a highly skilled Organic Chemist with specialized expertise in synthesis to join their innovative team in Paarl . This role is crucial for designing and executing complex multi-step syntheses of novel chemical entities for a variety of applications. You will be responsible for planning synthetic routes, optimizing reaction conditions, purifying products, and characterizing synthesized compounds using advanced analytical techniques.
This is an exceptional opportunity to contribute to cutting-edge chemical research within a well-equipped laboratory environment, working with a collaborative team dedicated to scientific discovery and innovation in the picturesque setting of Paarl .
Design and perform complex multi-step organic syntheses of target molecules, including natural products, pharmaceuticals, and advanced materials. Optimize reaction conditions to maximize yield, purity, and efficiency, while minimizing byproducts. Purify synthesized compounds using chromatographic techniques (e.g., column chromatography, HPLC) and crystallization. Characterize synthesized compounds using a range of analytical methods, including NMR spectroscopy , Mass Spectrometry (MS) , and FTIR. Troubleshoot synthetic challenges and develop innovative solutions to overcome obstacles.
Maintain detailed laboratory notebooks and prepare technical reports on synthetic projects.
Ph.D. in Organic Chemistry or a closely related field. Minimum of 4 years of post-doctoral or industry experience in synthetic organic chemistry. Proven expertise in a wide range of organic reactions and synthetic methodologies. Strong proficiency in modern spectroscopic techniques (especially 1D and 2D NMR ) and other analytical methods for compound characterization. Excellent problem-solving skills, meticulous attention to detail, and a strong grasp of reaction mechanisms.
BenefitsCompetitive annual salary and performance-based bonus opportunities. Comprehensive health, dental, and vision insurance. Support for professional development, including conference attendance and access to scientific literature. A collaborative and intellectually stimulating research environment in Paarl . The opportunity to work on challenging and rewarding synthetic chemistry projects.
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