Senior Process Scientist - gRNA process development

Questa posizione è in Chiesi Group

Il processo di selezione sarà interamente gestito Chiesi Group.

-
- # Senior Process Scientist - gRNA process development

** Date:
** 3 Jul 2026

** Department:
** GRD Biotech Research & Product Development

** Business Area:
** R&D, Pharmacovigilance & Regulatory Affairs

** Job Type:
** Direct Employee

** Contract Type:
** Permanent

*
* Location:

** Parma, IT

**
* ###
*** About us**
* Chiesi is an international research-focused biopharmaceutical group with 90 years’ experience, operating in more than 30 countries, with its Headquarter in Parma, Italy. More than 8,000 employees across the group are united by a singular purpose: promoting a healthier world for our people, patients, and the planet. This is what drives us as we research, develop, and market innovative drugs across our main therapeutic areas.

[Discover more here.](#)

At Chiesi we are thinking generations ahead, driving sustainable innovation with purpose. This fosters a culture of reliability, transparency, and ethical behaviour at every level. As a Benefit Corporation and a certified B Corp, we have embedded sustainability in our bylaws and continuously measure our impact.

Diversity and inclusion are at the heart of who we are. We believe our differences make us stronger. We are a vibrant ecosystem of passionate, talented individuals united by strong values, each bringing unique perspectives that help us to continuously challenge the status quo for the better.

###
*** Chiesi Global Rare Diseases**
* Chiesi Global Rare Diseases is a Chiesi Group’s business unit established in February 2020 and focused on research, development and commercialization of treatments and patient support services for rare and ultra-rare disorders, many of whom have limited or no treatments available.

This unit is based in Boston, Massachusetts, with a strong synergy with the headquarters in Parma.

Rare unit has a focus on research and product development for lysosomal storage diseases, rare hematology, ophthalmology disorders and rare immunodeficiencies. The unit is also a dedicated partner with global leaders in scientific research, patient advocacy and care. [Discover more here](#).

###
*** What we are looking for**
* ##
** This is what you will do*
* Chiesi Global Rare disease is recruiting a Senior Process scientist with deep expertise in the development and production of critical RNA-based gene editing components.

In this role, you will be a key member of the CMC Extended Technical Team (ETT) supporting the CMC Technical leader while being responsible for process development and manufacturing oversight of gene therapy (GT) programs across GRD projects. You will contribute to advancing in vivo LNP programs from candidate selection though clinical development and toward commercial launch, while also supporting lifecycle management activities.

##
** You will be responsible for*
* * Define and lead the development plan for process development, manufacturing and controls strategy for synthetic nucleotide, acting as a subject matter expert (SME) for the assigned projects.

* Design and oversee the gRNA development work streams supporting technology transfers of manufacturing processes

* Acting as the lead for outsourced process development activities, including:

* Screening, selection and onboarding of suitable CROs/CDMOs; support in auditing and qualification

* Providing strong technical governance and oversight, of external partners, ensuring robust and scientifically sound execution of external activities while driving accountability and continuous improvement.

* Proactive troubleshooting and risk management

* Lead root cause investigations and deviation assessments

* Reviewing technical plans, batch records, SOP and reports generated at the CDMO

*…