Advisor Chemistry and Chemical Biology

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve.

This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. At Lilly, we serve an extraordinary purpose. For more than 150 years, we have worked tirelessly to discover medicines that make life better. These discoveries start in Lilly Research Laboratories, where our scientists work to create new medicines that will help solve our world’s greatest health challenges.

Protomer Technologies is a wholly owned subsidiary of Lilly, a startup within Lilly, that focuses on chemical biology, molecular switches and (oral) peptidic macrocycles platforms. This position is focused on deep technology development in chemical biology, specifically peptides and macrocycles with a particular focus on peptide libraries, and oral macrocyclic peptides. Protomer team engages in disease‑relevant biological systems in order to test preclinical and clinical pipeline of innovative medicines.

The candidate is expected to help develop strategy, direction and manage scientific group milestones and objectives based on an ambitious long‑term strategic plan which the candidate helps to develop. The ideal candidate is a significant contributor and leading a highly integrated, agile, and collaborative team effort and expected to manage the scientific portfolio, the business supporting the portfolio, and mentoring of junior scientists within the insulin engineering group al candidate is expected to have demonstrated success in similar roles with proven track record of leading both scientific rationale, planning and execution leading to success in making medicines.

• Lead projects in insulin engineering, chemical biology or peptide frameworks combining aspect of molecule design and conjugation at the interface of small molecules and peptides.
• Initiate and lead new projects, can formulate strategy and execute on the strategy organizing efforts for deep technical development and to accelerate projects internal to the team.
• Work collaboratively in the group to achieve a common goal but also provide independent perspective and scientific rationale and contribute to strategy and execution.
• Balance science and the business of science by delivering the small and large (peptides) molecule portfolio through responsible planning, execution, and completion of projects.
• Work on and lead (both directionally and operationally) molecule engineering efforts from lead identification to lead optimization and contribute along the way to phase 1b and beyond.
• Take on dedicated molecular engineering efforts towards targets of high conviction and utilize speed and prioritization to advance synthetic efforts both at Protomer and wider Lilly groups and through collaboration with the rest of LRL.
• Learn about and enhance the platform technology efforts at Protomer.
• Inspire people to collaborate in inventing great medicines by removing barriers, committing to high quality scientific hypotheses, and accelerating where possible.
• Keep safety as a top priority at all times, striving toward a proactive safety culture.
• Be an advocate for diversity and inclusion in our recruiting, retaining and developing scientists, with a commitment to coaching and development of…