Senior Analytical Biochemist; Mass Spectrometry

Senior Analytical Biochemist (Mass Spectrometry)

At Ingenza, we are a dynamic, passionate team of 50 scientists and innovators driven by a singular mission: turbocharging biological systems to solve the world’s biggest challenges. From life‑saving therapeutics to sustainable consumer products and industrial enzymes, we transform science into scalable, real‑world solutions for human health and the global environment. As a fast‑growing, value‑led SME, we combine scientific excellence with a genuinely supportive culture of integrity and collaboration.

Embedded within a vibrant, sociable team, you will lead by example from our brand‑new, state‑of‑the‑art facilities at the Edinburgh Technopole. Surrounded by nature trails, an on‑site café, and stunning views of the Pentland Hills, you’ll find the perfect balance of breakthrough science and a world‑class working environment. To thrive here, you will possess excellent multitasking skills and the agility to navigate a fast‑paced dynamic work environment.

In this position, you will step into a pivotal role at Ingenza as a Protein Characterisation and MS Specialist. You will combine high‑level technical expertise in protein and peptide mass spectrometry with project leadership, demonstrating a proactive initiative and outstanding teamwork skills to deliver key customer results in a timely and accurate manner. The successful candidate will have a proven ability to work closely with senior management, providing strategic technical updates, aligning analytical capabilities with commercial objectives and helping shape the long‑term scientific direction of our services.

• A PhD or Masters in Analytical Chemistry, Chemistry, Biochemistry, or a closely aligned subject.
• For Master’s level candidates, a minimum of four years of dedicated industrial experience is essential.

• Advanced LC-MS Operation: Deep technical knowledge and hands‑on experience working with high‑resolution LC-MS instrumentation (e.g. Q-TOF-MS, TQ-MS) for protein and peptide analysis.
• Structural Characterisation: A fundamental understanding of how accurate mass and MS/MS workflows can be leveraged to resolve complex structural characterisation challenges.
• PTM & Glycan Profiling: Proven experience with post‑translational modification (PTM) analysis and N‑released glycan analysis workflows relevant to biotherapeutic regulatory filing requirements.
• Method Innovation: A track record of evaluating and developing novel methodologies or technological advancements to expand and upscale analytical capabilities with hands‑on experience in method validation aligned with regulatory expectations.
• Complex Data Interpretation: Rigorous experimental standard to interpret, analyse, and QC complex MS data at both the intact mass and peptide level.
• Instrumentation Custody: Confidence in the routine maintenance, calibration, and troubleshooting of high‑resolution analytical instrumentation.
• Software Proficiency: Proven expertise utilizing Agilent software (such as Mass Hunter and Bio Confirm) and familiar with other online MS data processing tools for both macromolecule and small molecule analysis.
• Data Translation: Ability to distil complex analytical data into accessible, clear formats for non‑specialist stakeholders, constructing professional presentations to deliver insights to project teams and customers.
• Interdisciplinary
  
  Collaboration:
  
  Outstanding team skills, and proven ability to collaborate effectively across diverse scientific disciplines and functional departments (e.g., molecular biology, fermentation and downstream processing) to achieve critical project milestones and deadlines.
• Dynamic Delivery: Proven ability to multitask seamlessly across parallel projects, coping with short timelines and managing competing tasks without compromising accuracy or data integrity.
• Technical Writing: Expertise in scientific writing to generate comprehensive project reports, technical protocols, and SOPs within an industrial quality management framework.
• Biochemistry & Biocatalysis: Strong working knowledge of biochemistry, protein chemistry, and…