Associate Director

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH. Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH.

Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c). Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration.

To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

The Associate Director, Benefits plays a critical role in owning and advancing Madrigal’s benefits programs. This role is responsible for leading benefits plan operations, driving key initiatives, and ensuring programs are delivered effectively, compliantly, and with a strong focus on communications and the employee experience. This individual partners closely with Total Rewards leadership and cross-functional stakeholders to influence program direction and drive operational excellence.  

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** Key Responsibilities
*** Own and lead the execution and ongoing management of Madrigal’s benefits programs, ensuring alignment with business objectives and employee needs
* Oversee day-to-day administration of all health, welfare, and retirement programs, ensuring accuracy, compliance, and a high-quality employee experience
* Exceptional communication skills translating complex benefits information into clear, concise messaging that drives employee understanding
* Oversee the administration and case management of all leave and disability programs, partnering with employees, managers, HR, administrators, and carriers to ensure effective program delivery, timely case resolution, and clear guidance on leave policies, processes, and accommodations.
* Serve as the primary escalation point for complex benefits issues and employee inquiries
* Own vendor relationships, including performance management, service delivery, issue resolution, and optimization of partnerships
* Lead vendor-related initiatives, including implementations, transitions, and enhancements
* Lead cross-functional coordination with HR Operations, Payroll, Finance, Legal, and external vendors to ensure seamless and compliant benefits delivery
* Lead change management and process improvement to enhance efficiency, scalability, and the employee experience
* Ensure compliance with applicable federal, state, and local regulations (e.g., ERISA, ACA, COBRA, HIPAA), including oversight of audits, filings, and required notices
* Own and execute open enrollment, including planning, communications, employee education, and post-enrollment activities
* Oversee retirement programs, including 401(k) and NQDC plans, with accountability for compliance and vendor performance
* Lead the administration and continuous improvement of wellness and wellbeing programs
* Manage benefits-related financial processes, including purchase orders, invoice reconciliation and vendor coordination
* Analyze data and trends to drive insights and continuous program improvement
* Maintain plan documentation, SOPs, policies, and internal controls
* Support the execution of Madrigal’s…