Associate Director, Cellular & Mechanistic Pharmacology

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This range is provided by Insight Global. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

$/yr - $/yr

Annual Bonus

We are searching for the best talent for an Associate Director, Cellular & Mechanistic Pharmacology located in Spring House, PA.

Purpose: Translational Bio screening is a newly formed team within the Multiomics Discovery function of Discovery Technologies & Molecular Pharmacology (DTMP). We contribute to the progression of cross-modality drug discovery projects from target identification to clinical development. Join our team! We’re looking for a talented scientific leader with an immunology background, deep expertise in disease biology and cellular pharmacology, and a passion for finding innovative therapeutics to treat diseases with high unmet medical need.

You will be responsible for:

• Lead development of innovative cell-based assays for immunology-focused projects to identify and evaluate targets, and to progress hits and lead molecules.
• Act as a key liaison between DTMP and program teams, driving project strategy and execution, in partnership with cross-functional colleagues.
• Lead efforts to integrate translational and mechanistic biology with novel AI/ML methods to enable the discovery of novel therapeutics
• Manage and mentor a team of lab scientists.
• Analyze and present data at program team meetings, in-house seminars, leadership meetings and external scientific conferences, and publish research in high-quality journals.

Qualifications/Requirements:

• Ph.
  
  D. in Immunology, cell biology or equivalent with a minimum of 8 years of experience in a pharmaceutical industry setting developing and applying novel cellular assays is required.

• Proven track record in leading immunology-focused drug discovery programs across diverse modalities, in an industry setting.
• Deep expertise and proven accomplishments in de novo immunology cellular pharmacology assay development, complex immune cellular models and high-throughput technology platforms.
• Experience with generating and culturing translationally relevant cell models such as iPSC-derived cells, primary cells, and/or co-cultures.
• Expertise collecting and analyzing data using high dimensional approaches such as high content imaging, flow cytometry and/or RNAseq.
• Strong experience as a leader, problem solver and team collaborator able to facilitate understanding between biologists, chemists, and data scientists.
• A demonstrated ability to apply novel approaches to address complex biology questions, as evidenced through strong peer‑reviewed publications.
• Excellent written communication, verbal communication, and oral presentation skills.
• Demonstrated influence, negotiation, and conflict resolution skills.

• Expertise in assay automation and analysis workflows.
• Proficiency with CAS/CRISPR, lentivirus and/or RNAi approaches.
• Expertise developing assays in translational and advanced cellular systems such as 3D models.
• Exposure to neuroscience and/or oncology therapeutic areas.
• Experience working with and/or guiding external collaborators in industry or academia.

Compensation:

$137-205K

Exact compensation may vary based on several factors, including skills, experience, and education.

Benefit packages for this role will start on the 31st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.

Mid‑Senior level

Full‑time

Science

Pharmaceutical Manufacturing