Distinguished Scientist, Discovery-Oncology

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, and solutions are personal.

Through our expertise in Innovative Medicine and Med Tech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow,and profoundly impact health for humanity.

Learn more at  As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit. Job Function:
Discovery & Pre-Clinical/Clinical Development Job Sub Function:
Pharmaceutical Product R&D Job Category:
Scientific/Technology All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. About Oncology Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements.

Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Our Oncology team is focused on the elimination of cancer by discovering new pathways and modalities to finding treatments and cures. We lead where medicine is going and need innovators with an unwavering commitment to results. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

We are searching for the best talent for a Distinguished Scientist, in Oncology Discovery, Innovative Medicine, located in Spring House, PA. Johnson & Johnson Innovative Medicine Oncology Discovery seeks an outstanding and highly motivated leader to join our team focused on creating best-in-class therapeutics for prostate cancer treatment. This position will lead a cross-disciplinary team responsible for developing a robust platform to engineer and optimize T-cell engagers (TCEs), and small molecule therapeutics.

Candidates should have expertise in cancer biology or immunology, and the mechanisms required to trigger robust anti-tumor response. Additionally, candidates must demonstrate direct experience in small/large molecule design and/or combination strategies to overcome solid tumor microenvironment. Furthermore, knowledge of current assays required to characterize optimal T-cell functional performance is a requirement. A successful candidate is expected to drive future innovation around TCE design by identifying enabling technologies through either internal or external efforts.

Candidates must demonstrate prior program leadership experience in industry and must have a track record of excellence in managing teams and developing scientific talent.

• Lead a team of scientists in nominating T-cell engagers (TCE) and costimulatory molecules for the treatment of prostate cancer
• Lead a team of scientists to develop state-of-the-art assays that enable the identification of optimal TCE candidates to maximize therapeutic potential and durability in solid tumors
• While delivering on prioritized goals, foster a culture of scientific excellence and innovation that lead to next generation TCE/costim platforms
• Partner with leaders in other therapeutic areas to select optimal binders, molecular configuration and delivery strategies
• Organize business development and diligence efforts with internal and external partners to pursue opportunities associated with next gen TCE or small molecule therapies
• Eliminate barriers to collaboration across work streams and functions by encouraging a culture of open communication and transparency
• Contribute to intellectual property, public presentations, and manuscript writing
• Identify partnerships in academia to compliment key research initiatives
• Mentor scientists on the team, and promote personal and professional development
• Contribute to leadership of PDAS discovery team by…