Senior Manager, Bioengineering & Cellular Technologies

Location: Spring House

This job is with Johnson & Johnson, an inclusive employer and a member of my Gwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and Med Tech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn

more at
Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub     Function:
Biological Research

Job Category:
People Leader

All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at
We are searching for the best talent for a Senior Manager, Bioengineering & Cellular Technologies in Spring House, PA.

Purpose:

The Discovery Technology & Mechanistic Pharmacology Team at Johnson & Johnson is seeking a highly motivated and innovative Senior Manager to lead our Bioengineering and Cellular Technologies team. This role will drive the design and implementation of advanced biofabricated tissue models, microphysiological systems, and cellular platforms to accelerate hit identification, lead discovery, lead optimization for small molecules and biologics, and in vitro safety assessment.

The successful candidate will combine expertise in bioengineering, tissue fabrication, and cellular model development with strong leadership skills to build and manage a multidisciplinary team. In addition to supporting assay cell culture needs for HTS and lead optimization, this team will develop cutting-edge technologies including CRISPR-engineered cell lines, iPSC-derived models, organoids, complex co-culture systems, and primary immune cell platforms to enable high-throughput compound screening and mechanistic studies.

The incumbent should possess strong collaboration and written/verbal communication skills and a positive attitude to interact with multiple stakeholders.  This is a lab-based position, and the candidate should demonstrate team leadership, scientific leadership at the bench and with data analysis, and be adept at multitasking with agility to swiftly handle shifting priorities and demands.
You will be responsible for:
Strategic Leadership   Define and execute the vision for bioengineering and cellular technology innovation to support drug discovery programs.
Lead and mentor a team of scientists and bioengineers specializing in cell line development, tissue engineering, and advanced cellular models.

Translational Cellular Model, Assay, and Technology Development   Design and implement biofabricated tissue models and microphysiological systems compatible with automated screening platforms.
Oversee development of CRISPR-edited cell lines, iPSC-derived systems, 3D models, and complex multicellular models for lead discovery and pharmacological profiling.
Design scalable assays with translationally relevant functional readouts using high content imaging, flow cytometry or other cutting-edge readout technologies.
Integrate advanced cellular technologies with high-throughput-screening workflows and data analytics.

Communication, Collaboration & Influence   Develop compelling scientific presentations and reports for internal review meetings and scientific journals
Partner with therapeutic area teams, automation engineers, and data scientists to deliver robust, scalable solutions.
Represent the team in cross-functional strategy discussions and external collaborations.

Innovation & Compliance   Stay at the…