Analytical Scientist - Mass Spectrometry

Join GSK's Extended Characterization Europe team as an Analytical Scientist, supporting the analytical development and characterisation of biopharmaceutical molecules. This predominantly laboratory-based role will use LC-MS and LC-MS/MS to generate scientific understanding that supports the development and control of new drug substances and products. You will work independently and collaboratively across Discovery and CMC Development teams, combining strong scientific judgement, data analysis, communication and organisation to help deliver a novel pipeline of medicines to patients.

• Plan, execute and interpret LC-MS and LC-MS/MS experiments for the characterisation of biopharmaceutical molecules.
• Develop, optimise and troubleshoot analytical methods, experiments and instrumentation.
• Investigate molecular structure, product quality attributes and post-translational modifications to support the identification and assessment of critical quality attributes.
• Support early-phase programmes through forced degradation studies, comparability assessments, process understanding and technical transfer.
• Critically evaluate complex analytical datasets, draw scientifically robust conclusions and recommend appropriate next steps.
• Communicate findings clearly, prepare high-quality technical documentation and maintain high standards of data integrity, quality and laboratory safety.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting‑edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success.

We're uniting science, technology, and talent to get ahead of disease together.

Find out more:
Our approach to R&D.

• PhD, MSc or equivalent relevant experience in Analytical Chemistry, Chemistry, Biochemistry, Pharmaceutical Sciences or a related discipline.
• Experience of LC-MS or LC-MS/MS method development and execution for biopharmaceuticals in a pharmaceutical or biotechnology setting.
• Good understanding of protein biochemistry, post‑translational modifications and the relationship between molecular structure, function and product quality attributes.
• Ability to independently plan and execute analytical experiments and troubleshoot scientific and technical challenges.
• Experience working in matrix teams and delivering time‑bound, multi‑project work packages with strong organisation and prioritisation.
• Strong data interpretation, written and verbal communication skills, with a commitment to data integrity, scientific standards, safe laboratory practice and effective documentation.

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

• Knowledge of protein glycosylation and analytical workflows for N‑linked glycan analysis.
• Understanding of antibody sequence and structure‑function relationships and critical quality attributes.
• Experience with liquid‑handling automation systems.
• Experience with mass spectrometry data‑analysis software such as Protein Metrics or equivalent platforms.
• Experience handling large datasets and conducting statistical analysis using software such as JMP or SIMCA.
• Understanding of biopharmaceutical manufacturing processes and confidence working across teams with shared laboratory instrumentation., Analytical Chemistry, Analytical Instrumentation, Analytical…