Director, Clinical Genomics Laboratory

UPMC Magee is seeking a PhD, MD or DO Geneticist at the Assistant/Associate Director or Director-level in Pittsburgh, Pennsylvania. The Assistant Director will support the UPMC Clinical Genomics Laboratory (UCGL) at UPMC Magee Women's Hospital, focusing on molecular testing services such as whole exome sequencing, NGS, and hereditary cancer screening. The selected candidate will hold a faculty appointment at the University of Pittsburgh while contributing to technical leadership, compliance, and clinical casework.

Practice Info

• Supports the UPMC Clinical Genomics Laboratory (UCGL) at UPMC Magee Women's Hospital
• Laboratory performs prenatal, constitutional, and oncology molecular testing
• Provides comprehensive services including whole exome sequencing, disease specific genomic panels, hereditary cancer screening, carrier screening, and pharmacogenomic analysis using advanced technologies such as next generation sequencing (NGS)

Responsibilities

• Contribute to technical leadership, compliance oversight, case sign out, assay development, client consultation, and education/training
• Evaluate and report clinical genetics and genomics cases, including carrier screening, Sanger sequencing, quantitative RT PCR, and NGS
• Provide technical and compliance oversight for the clinical genomics laboratory; review and approve procedures and QA/QI plans with the CLIA/CAP Lab Director
• Assist in developing, validating, implementing, and maintaining laboratory procedures
• Ensure ongoing compliance with CLIA, CAP, and other regulatory requirements
• Collaborate with UPMC and University of Pittsburgh partners, including UPMC Children's Hospital, on service development and business planning
• Consult with clinicians and clients regarding test selection and result interpretation
• Participate in research aligned with the clinical and public health missions of UPMC and the University of Pittsburgh, collaborate with faculty, contribute to teaching, and publish in peer reviewed journals

Qualifications

• PhD, MD, or DO in Clinical Laboratory Science, Genetics, Molecular Biology, or related field
• ABMGG board certified or board eligible in Laboratory Genetics and Genomics or Clinical Molecular Genetics
• Minimum 3 years clinical laboratory experience
• Expertise in exome/genome analysis and interpretation of sequence and CNV data from NGS
• Excellent written and oral communication skills
• Demonstrated problem solving and operational leadership
• Proficiency with LIMS and genomic data analysis tools
• Maintain active ABMGG certification and remain up to date with advances in genetics and molecular genomics