Sr. Imaging Science Engineer - Pleasanton, CA

Sr. Imaging Science Engineer - Pleasanton, CA

Calyxo, Inc. is a medical device company headquartered in Pleasanton, California, USA, founded in 2016 to address the profound need for improved kidney stone treatment. Kidney stone disease is a common, painful condition that consumes vast amounts of healthcare resources each year. Our team is led by executives and investors with a proven track record of commercializing paradigm‑shifting devices to meet unmet needs within urology.

Calyxo is seeking a highly skilled and innovative Imaging Science Engineer, responsible for driving the design, testing, and analysis of endoscope camera and illumination systems. The ideal candidate will lead the optical design and quantitative evaluation of endoscope image and video quality for end‑to‑end systems and subsystems. This individual will be a key member of a multidisciplinary engineering team to support existing product lines while driving the development of next‑generation technologies.

The role also requires ensuring that all engineering efforts comply with industry standards and regulatory requirements while aligning with strategic business objectives.

• Design camera and illumination optical systems/subsystems for endoscopy and perform detailed quantitative analyses of their imaging & video performance.
• Work with cross‑functional teams to define requirements for image and video quality.
• Drive in‑process and end‑of‑line optical test methodology used in component and device manufacturing.
• Work with clinical engineering and product management to translate user feedback on visualization quality into bench‑testable design improvements.
• Organize design reviews to ensure optimal imaging design performance across disposable instruments, capital hardware, and software interfaces.
• Create change orders, test protocols/reports, and design documents.
• Complete Design Verification testing and risk management activities.
• Interact with suppliers and internal operations representatives to perform root cause investigation, component lifecycle management and continuous improvement.
• Create, operate and maintain an optical test bench and testing laboratory environment complying with Calyxo’s internal Quality Management System.
• Contribute to the technology roadmap for visualization and related research endeavors.
• Contribute to a culture of continuous improvement and innovation among engineering and cross‑functional teams.
• Collaborate with cross‑functional teams to bring prototypes to the market.
• Mentor junior and non‑specialist engineering talent, promoting a collaborative and high‑performance work environment.

• Director, Vision & Sensor Systems

• MS in Imaging Science, Optical Engineering, Electrical Engineering, Physics or a related technical field. PhD preferred and 4+ years of experience in product development related to camera and illumination system design/characterization.
• Deep technical expertise in camera and illumination system quantitative analysis, including relevant standards (e.g. ISO 8600, 12233, 14524 and 15739) and colorimetry, including practical application of CIE ΔE and ΔC measurement.
• Practical experience in hands‑on laboratory optics, including use of optical test targets, backlights, optomechanics, meters, sensors and other test equipment.
• Experience performing photometric and radiometric quantitative analyses of illumination systems, including power meters, spectroradiometers and spectrophotometers.
• Practical working knowledge of analog and digital electronics fundamentals.
• Experience using Imatest software for image quality assessment.
• Proficiency in Python or alternative scripting language for image/video analysis, hardware control and test automation strongly preferred.
• Expertise in optical/optomechanical component and system design. ZEMAX (or alternative ray‑tracing software) and Solid Works (or alternative CAD software) preferred.
• Experience leading external vendors and contract manufacturers in the development of custom imaging solutions.
• Strong problem‑solving skills and experience working as part of multifunctional technical project teams through all…