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Research Scientist - Pharmaceutical Chemistry

Job in Polokwane, Limpopo, South Africa
Listing for: Placements24
Full Time position
Listed on 2026-09-12
Job specializations:
  • Research/Development
    Drug Discovery, Pharmaceutical Science/ Research, Medicinal Chemist, Research Scientist
Job Description & How to Apply Below

About the Role

Our client is seeking a skilled Research Scientist specializing in Pharmaceutical Chemistry to join their vibrant R&D department in Polokwane . This role involves contributing to the synthesis and optimization of novel drug candidates, working closely with medicinal chemists and biologists. You will utilize state-of-the-art facilities and methodologies to accelerate the drug discovery process. This position offers an excellent opportunity for a talented chemist to make significant contributions within a collaborative and innovative environment located in Polokwane .

Key Responsibilities
  • Synthesize complex organic molecules and intermediates for drug discovery programs.
  • Develop and optimize synthetic routes for target compounds.
  • Purify and characterize synthesized compounds using analytical techniques (e.g., NMR, LC-MS, HPLC).
  • Collaborate with medicinal chemists to design and synthesize new chemical entities (NCEs) with improved properties.
  • Maintain accurate laboratory records and contribute to research reports and presentations.
  • Ensure compliance with safety regulations and laboratory best practices.
Requirements
  • Ph.D. in Organic Chemistry, Medicinal Chemistry, or a related field.
  • Minimum of 3 years of post-doctoral or industry experience in synthetic organic chemistry.
  • Proven expertise in synthetic organic chemistry, including multi-step synthesis and reaction optimization.
  • Hands-on experience with modern purification and characterization techniques.
  • Familiarity with drug discovery processes and medicinal chemistry principles.
  • Strong problem-solving skills and the ability to work effectively in a team.
Benefits
  • Competitive salary and comprehensive health, dental, and vision insurance.
  • Performance bonuses and opportunities for career advancement.
  • Support for professional development and attendance at scientific meetings.
  • Access to modern research facilities and equipment in Polokwane .
  • A collaborative and stimulating research culture.
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