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Research Scientist - Medicinal Chemistry

Job in Gqeberha, Port Elizabeth, 6000, South Africa
Listing for: Placements24
Full Time position
Listed on 2026-10-12
Job specializations:
  • Research/Development
    Drug Discovery, Medicinal Chemist, Research Scientist, Pharmaceutical Science/ Research
Job Description & How to Apply Below
Location: Gqeberha

About the Role

Our client is seeking a talented Research Scientist specializing in Medicinal Chemistry to join their dynamic team in Port Elizabeth . This role is crucial for the discovery and development of novel therapeutic agents, focusing on the design, synthesis, and optimization of small molecules. You will work collaboratively within a multidisciplinary team, contributing your expertise in synthetic organic chemistry to identify and develop promising drug candidates that address unmet medical needs.

Key Responsibilities
  • Design and synthesize novel small molecules with potential therapeutic activity using advanced organic chemistry techniques.
  • Optimize lead compounds through iterative structure-activity relationship (SAR) studies.
  • Characterize synthesized compounds using analytical methods such as NMR, LC-MS, and HPLC.
  • Collaborate with biologists and pharmacologists to evaluate the efficacy and safety of drug candidates.
  • Maintain detailed laboratory notebooks and prepare reports on synthesis and characterization data.
  • Stay current with advances in medicinal chemistry and drug discovery technologies.
Requirements
  • Ph.D. in Medicinal Chemistry, Organic Chemistry, or a related field.
  • Demonstrated experience in the synthesis of complex organic molecules.
  • Strong understanding of SAR principles and drug discovery processes.
  • Proficiency in modern analytical techniques for compound characterization.
  • Ability to work effectively in a collaborative, team-oriented research environment.
  • Excellent problem-solving skills and a commitment to scientific rigor.
Benefits
  • Competitive annual salary and a structured bonus program.
  • Comprehensive health and wellness benefits.
  • Opportunities for professional development and attendance at scientific conferences.
  • Access to modern synthetic chemistry laboratories and analytical instrumentation.
  • A supportive and collaborative work environment focused on innovation in drug discovery.
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