Senior Analytical Chemist - Pharmaceutical

Our client is seeking a highly experienced Senior Analytical Chemist to join their Quality Control and Research & Development department in Pretoria. This critical role involves developing, validating, and implementing analytical methods for pharmaceutical products, ensuring compliance with regulatory standards. You will utilize a wide range of advanced analytical instrumentation to test raw materials, in-process samples, and finished products. The ideal candidate possesses a deep understanding of analytical techniques, strong regulatory knowledge (e.g., GMP, ICH), and a meticulous approach to data integrity and quality assurance, contributing to the safety and efficacy of pharmaceutical products developed and manufactured locally.

• Develop, validate, and transfer analytical methods for new and existing pharmaceutical products according to regulatory guidelines.
• Perform routine and non-routine analysis of raw materials, intermediates, and finished products using various analytical techniques.
• Operate and maintain advanced analytical instrumentation, including HPLC, GC, MS, UV-Vis, and dissolution testers.
• Investigate and troubleshoot analytical method failures or out-of-specification (OOS) results.
• Ensure all analytical activities are performed and documented in compliance with Good Manufacturing Practices (GMP) and other relevant regulatory requirements.
• Collaborate with formulation scientists and regulatory affairs teams to support product development and registration.

• M.Sc. or Ph.D. in Analytical Chemistry, Pharmaceutical Sciences, or a related field.
• Minimum of 6 years of experience in pharmaceutical analytical chemistry, with a strong focus on method development and validation.
• Extensive hands-on experience with various chromatographic techniques (HPLC, UPLC, GC) and spectroscopic methods.
• Thorough understanding of ICH guidelines, GMP, and other relevant regulatory requirements for pharmaceutical testing.
• Proven ability to troubleshoot complex analytical issues and implement effective solutions.
• Excellent technical writing skills for protocol and report generation in a Pretoria-based laboratory.

• Attractive salary package with performance-related incentives.
• Comprehensive health coverage and retirement benefits.
• Support for continuing education and professional certifications.
• Access to cutting-edge analytical laboratories and instrumentation.
• A stable and professionally rewarding work environment within a leading pharmaceutical research organization.