Manager, Accounting

Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.

It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.

Led by Tassos Gianakakos, Jay Edelberg, M.D., Ph.D., and Bob McDowell, Ph.D., Kardigan’s co‑founders have reunited after leading Myo Kardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.

We have a cutting-edge discovery and translational research platform, a pipeline of late‑stage candidates, and an industry‑leading team that is driven to improve the lives of patients.

At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals.
Driven by patients and their families
, we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in being authentic
—leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn
, we encourage the highest levels of curiosity and are open to changing our minds. We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.

These values are the foundation of our work, empowering us to make a real difference, every day.

Position Title: Manager, Accounting

Department: Finance & Accounting

Reports To: Senior Director, Accounting

Location: Princeton, NJ – On-site 4 days per week (Mon to Thurs)

Kardiganis seeking a skilled and detail-oriented Manager, Accounting , to manage and oversee the company’s accounting functions. This position primarily focuses on managing and independently executing complex aspects of the company’s accounting operations, ensuring compliance with GAAP, financial reporting accuracy, and efficient financial processes. In addition, the role will also assist in processing payroll and payroll related matters, accounts payable and purchasing.

This is an exciting opportunity for a professional with hands‑on experience and a strong accounting background to have a meaningful impact on financial operations within a growing organization. The ideal candidate will play a critical role in driving process improvements and working alongside key internal teams to enhance overall business performance.

• Accounting Leadership: Manage and oversee the company’s general ledger, ensuring accuracy and compliance with GAAP, internal policies, and regulatory guidelines while leading month-end and year-end close processes, including preparing and reviewing more complex reconciliations, journal entries, and accruals. Own and resolve complex, judgmental balance sheet reconciliations, including R&D and clinical trial expense accruals, prepaid balances, and intercompany accounts, by identifying root causes rather than simply tying out balances.
  
  Review and analyze financial data to maintain accuracy and integrity in records, assist in preparing financial statements for business decision‑making, and assist with proper accounting treatment, including evaluation of non‑routine or judgmental transactions. Research, document, and present the company’s position accounting matters (e.g., revenue recognition, leases, R&D cost accrual and capitalization), in clear, well‑supported memos.
• System Integration and Management: Lead…