Senior Director, Biostatistics

Sep 24, 2026

$257,000 - $335,000/year

About Us

Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.

It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.

Led by Tassos Gianakakos, Jay Edelberg, M.D., Ph.D., and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading Myo Kardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.

We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.

At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals.
Driven by patients and their families , we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in being authentic —leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn , we encourage the highest levels of curiosity and are open to changing our minds.

We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.

These values are the foundation of our work, empowering us to make a real difference, every day.

About the Job

Level: Senior Director

Hiring Manager: Executive Director, Head of Biostatistics

Location: Princeton, NJ

Classification: Hybrid – On-site 4 days per week (Mon to Thurs)

Travel: As needed, up to 15%

About the Team

Kardigan’s Biometrics organization is the analytical backbone of our development portfolio. Working closely with Clinical Development, Medical, Regulatory Affairs, Clinical Operations, and Data Management, the team shapes how our studies are designed, how evidence is generated, and how results are interpreted and communicated to health authorities. Biostatistics is a scientific partner in program strategy, not a downstream delivery function.

We are building a team that pairs methodological depth with practical judgment and a strong sense of ownership. Team members have the opportunity to influence trial design and development decisions early, apply innovative analytical approaches in a regulatory context, and help establish the standards and ways of working that will carry Kardigan through multiple registration-directed programs. Our work helps Kardigan move with urgency while safeguarding scientific and analytical integrity, ultimately supporting our mission to bring potentially transformative treatments to people living with cardiovascular disease.

Job Overview

Kardigan is seeking a Senior Director, Biostatistics, to serve as the lead statistician for one or more of our late-stage cardiovascular development programs. Reporting to the Executive Director, Head of Biostatistics, this individual owns the statistical strategy and analytical deliverables for their assigned programs, from study design through analysis, reporting, and submission support.

This is a hands-on scientific leadership role. The Senior Director is expected to bring methodological rigor and sound judgment to program design questions, to represent Biostatistics credibly on cross-functional program teams, and to serve as the statistical voice for their programs’ health authority interactions, aligning with…