Global Director, Clinical Project Management

Syst Immune is a leading and well‑funded clinical‑stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi‑specific, multi‑specific antibodies, and antibody‑drug conjugates (ADCs). Syst Immune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, Syst Immune has a robust preclinical pipeline of potential cancer therapeutics in the discovery and IND‑enabling stages, representing cutting‑edge biologics development.

We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

The successful candidate will oversee and coordinate global clinical trials from initiation through to completion, ensuring compliance with regulatory requirements, managing study timelines and budgets, and fostering effective communication among stakeholders. This role involves ensuring compliance

Us with regulatory requirements, managing study timelines and budgets, and fostering effective communication among stakeholders. The global Director, Clinical Project Management will play a critical role in delivering high‑quality data and ensuring the success of clinical studies.

• Oversee the planning and execution of global clinical trials
• Develop and implement study protocols, timelines, and budgets
• Manage all aspects of clinical trial operations, including site selection, initiation, monitoring and closeout
• Ensure compliance with Good Clinical Practice (GCP) and regulatory guidelines
• Coordinate with cross‑functional teams, including investigators, vendors and regulatory bodies
• Monitor trial progress and manage data collection to ensure accuracy and integrity
• Identify and mitigate project risks
• Oversee a team of regional CPMs, CRAs and CTAs
• Ensure the preparation and submission of regulatory documents are compliant with local regulatory standards and maintained per good clinical practice
• Conduct regular meetings with study teams and provide updates to stakeholders
• Coordinate with external vendors and partners involved in the trial
• Support development of key process initiatives and SOPs internally
• Oversee vendors supporting trial execution

• Bachelor’s degree in Life Sciences, Nursing or a related field
• Minimum of 10 years of experience in clinical trial management, including at least 5 years in a direct line management role
• Strong understanding of GCP and regulatory requirements
• Excellent organizational and project management skills
• Proven ability to lead cross‑functional teams and manage multiple priorities
• Strong communication and interpersonal skills
• Ability to work collaboratively in a team‑oriented environment
• Flexibility and adaptability to changing priorities and workload
• Master’s degree in a related field or clinical research certification (e.g., ACRP or SOCRA)
• Experience with electronic data capture (EDC) systems and clinical trial management software
• Prior experience in running or supporting oncology clinical trials – a plus
• Previous experience in a sponsor or CRO environment

• Princeton, NJ hybrid – 3 days in office
• Overnight travel ~25%

The expected base salary range for this position is $180,000–$230,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience and skills. While most offers typically fall within the low to mid‑point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.

We offer a comprehensive benefits package including 100% paid employee premiums for medical, dental and vision; STD, LTD; a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years; 15 PTO days per year, sick leave, plus 11 paid holidays and more.

We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.

Syst Immune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.