Associate Director, Clinical Supply Management

Princeton, NJ (US) and Palo Alto, CA (US)

Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people.

Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.

HARMONi:
Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.

HARMONi-3:
Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

HARMONi-7:
Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.

HARMONi-GI3:
Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.

The Associate Director, Clinical Supply Management supports the Senior Director in leading the full scope of global clinical supply chain responsibilities. The role translates functional strategy into disciplined execution across demand and supply planning, inventory management, packaging and labelling, distribution, returns and destruction, cross-border compliance, and GxP operations. Acting as a key delegate for the Senior Director, the (Associate) Director provides a layer of management for direct reports, establishes clear priorities and performance expectations, develops team capability, and drives operational excellence through standardized processes, meaningful metrics, proactive risk management, and continuous improvement.

The role partners closely with Clinical Operations, Commercial, CMC, Quality, Regulatory, Finance, Legal, Procurement, Medical Affairs and Program Management, and oversees external partners including Contract Development and Manufacturing Organizations (CDMOs), IXRS providers and specialist service providers.

• Supports the Senior Director in developing functional strategy, operating plans, budgets, governance and performance objectives across global clinical supply chain activities
• Leads day-to-day execution for new and ongoing studies and products, ensuring robust forecasting, supply planning, schedule adherence, inventory optimization, global logistics and sustained GxP compliance
• Serves as a delegate for the Senior Director in cross-functional forums, governance meetings, supplier reviews and issue escalation, providing clear recommendations and ensuring timely follow-through.
• Manages and develops direct reports, translating functional priorities into individual objectives, balancing workloads, coaching performance, supporting career development and ensuring appropriate succession and capability plans.
• Creates an effective management layer by coordinating team activities, reinforcing accountability, removing operational barriers and escalating material risks or decisions to the Senior Director.
• Overseeing the Clinical Supply Management (CSM) team, the Associate Director interprets complex clinical protocols, development plans and commercial demand forecasts, working with CMC and internal and external partners to develop packaging, labelling, supply and resupply strategies, timelines and plans.
• Supports the accountability of CSM team to oversee packaging, labelling, release, distribution, resupply, returns, reconciliation and destruction activities across global locations
• Develops and maintains supply…