Scientific Associate Director - Toxicology

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Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Location:

New Brunswick, Lawrenceville, Princeton, NJ;
San Diego, Brisbane, CA;
Cambridge, Mass;
Seattle, WA

• Oversight of the nonclinical safety evaluation programs for selected drug candidates.
• Assist in the proper design and timely reporting of toxicity studies (GLP/nonGLP), including single- and repeat-dose toxicity, investigative toxicity, and other toxicity studies as required.
• Act as a Nonclinical Safety representative on early- and late-stage project development teams.
• Provide scientifically and strategically sound nonclinical development plans to management and development teams.
• On an as-needed basis, interact with regulatory agencies worldwide on issues of nonclinical safety evaluation.
• Write and critically review submission documents, such as CTD sections for INDs and NDAs, IBs, PIPs, briefing books to support clinical trials and drug registration globally.
• Participate in discussions with internal development teams and/or regulatory agencies to address safety findings and provide safety assessments.
• Evaluate, propose, and apply new scientific methodology to enhance scientific excellence and/or productivity in Nonclinical Safety. Work collaboratively across disciplines to identify, characterize, and resolve target/compound based toxicities.
• Represent BMS in external scientific and regulatory collaborations, committees and consortia.
• Gain broad-based exposure to the various functional areas within Nonclinical Safety with an opportunity to perform independent research as appropriate.
• Collaborate with the Discovery organization to help evaluate toxicity of drug candidates.
• Ensure compliance with Good Laboratory Practice, Standard Operating Procedures, and study protocols in conducting nonclinical studies, when applicable. Ensure compliance with all company/departmental policies, particularly those relating to animal welfare and safety.
• Embrace/demonstrate BMS Core Values to create an atmosphere of scientific excellence, open communication, and creativity in order to maximize productivity.

• Bachelor's Degree and 15+ years of academic/industry experience
• Master's Degree and 12+ years of academic/industry experience
• PhD and 8+ years of academic/industry experience
• Plus 6+ years of leadership experience

• 10+ years regulatory toxicology/development experience.
• Knowledge of biochemical and mechanistic toxicology, immunology, pharmacology, biology of disease, and/or experimental pathology. Experience designing and interpreting in vitro and in vivo studies exploring mechanisms of toxicology involving biochemical, immunological, functional, molecular, and/or structural endpoints.
• Effective written and oral communication skills, especially as they pertain to writing clear, and accurate documents and presenting data.
• Individual must be able to manage multiple research activities, provide and accept input on data interpretation, foster a spirit of team effort, and be able to work well with others.
• Ability to interpret and apply available toxicity data to assess relative risk or hazard to humans.

• Brisbane - CA - US: $205,490 - $249,003
• Cambridge Crossing: $205,490 - $249,003
• New Brunswick - NJ - US: $178,690 - $216,527
• Princeton - NJ - US: $178,690 - $216,527
• San Diego - CA - US: $196,550 - $238,177
• Seattle - WA: $196,550 - $238,177

Additional incentive cash and stock opportunities (based on eligibility) may be available.

The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit

• Health Coverage:
  Medical, pharmacy, dental, and vision care.
• Wellbeing Support:
  Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support,…