Sr Research Associate, Antibody Characterization

Sr Research Associate, Antibody Characterization

USA - Quincy, MA

We are seeking a motivated individual to join our team and expand our antibody characterization department. Using state-of-the-art technologies and workflows, this Senior Research Associate will work with the Antibody Characterization team to ensure project‑specific deliverables are met across a diverse panel of discovery campaigns and contract services. The role involves wet‑lab experimental design, execution, and data analysis for multiple custom antibody development projects incorporating various biologics assay formats.

• Develop, run, and troubleshoot antibody characterization experiments using advanced label‑free analytical techniques (e.g., BLI and SPR) in a variety of formats to evaluate binding kinetics, ligand blocking, and binning.
• Perform titer testing, screening, and antibody validation by ELISA and high‑throughput multicolor flow cytometry.
• Run and troubleshoot cell‑based functional assays.
• Handle sample inventory tracking and assist with automation integration into the department.
• Concurrent execution of multiple antibody discovery projects requiring wet‑lab activities, data analysis, report generation, and preparation of deliverables.
• Record and communicate experimental details, draft reports, and deliver data with a high level of integrity and ethics.

• Bachelor’s degree in molecular biology, biochemistry, or a related discipline with a minimum of 4–5 years of related experience, or 3 years experience with MS.
• Strong understanding of antibody discovery, preferably focusing on assay development and protein characterization.
• Previous experience with SPR is required; experience with a Carterra instrument is preferred.
• Previous experience with BLI is strongly preferred.
• Experience with cell culture is preferred.
• Direct experience with ELISA and multicolor flow cytometry is advantageous.
• Ability to effectively troubleshoot and optimize processes to meet a wide range of project needs.
• Ability to work independently, collaborate, and communicate effectively within and across departmental teams.
• Exceptional written and verbal communication skills.
• Highly organized, detail‑oriented, and able to operate in a fast‑paced and growing environment.

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA. At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon‑based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.